Phase 1 Infant Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1
PEARL (PrEnAtal Enzyme Replacement Therapy for Lysosomal Storage Disorders)
Pompe Disease (Infantile-Onset)MPS VIIMPS I+6 more
University of California, San Francisco10 enrolled1 locationNCT04532047
Recruiting
Phase 1
Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies
Genetic epilepsyDevelopmental and Epileptic EncephalopathiesEpileptic Spasms+1 more
Heather Olson10 enrolled1 locationNCT06700811
Recruiting
Phase 1Phase 2
PK/PD of Digoxin in Infants With SVHD
Single VentricleInfant ConditionsInfant, Newborn, Diseases+1 more
Duke University20 enrolled2 locationsNCT06613477
Recruiting
Phase 1
Slow Introduction of Nutrition for Ill Malnourished Children
Malnutrition, ChildMalnutrition, Severe AcuteMalnutrition, Infant
The Hospital for Sick Children135 enrolled2 locationsNCT06846749
Recruiting
Phase 1Phase 2
Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants
Infant, Premature, DiseasesCirculatory and Respiratory Physiological Phenomena
Instituto de Investigación Hospital Universitario La Paz30 enrolled3 locationsNCT06878742
Completed
Phase 1
Intravenous pentoxifylline as adjunct therapy in preterm infants with late-onset sepsis or necrotizing enterocolitis
Pentoxifylline pharmacokineticsPreterm infant
Tobias Strunk23 enrolled1 locationACTRN12616000219482
Not Yet Recruiting
Phase 1
ProVac:Probiotic adjuvant to enhance the efficacy of pnemococcal vaccination: A pilot study.
Healthy infant immune response to the PCV13 pneumococcal vaccination
Associate Professor Mimi Tang30 enrolled1 locationACTRN12613000368730
Completed
Phase 1
The effect of active chest physiotherapy techniques on regional ventilation on preterm infants on ventilatory support.
Preterm infants with respiratory disease on ventilatory support
Mater Health Services20 enrolled1 locationACTRN12606000211561
Completed
Phase 1
Determination of differential effects of 3 positions on lung function in preterm infants.
Preterm infants requiring ventilatory support
Mater Health Services54 enrolled1 locationACTRN12606000210572