Phase 2 Inflammatory Clinical Trials
57 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 57 trials
Recruiting
Phase 2
FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis
Inflammatory Bowel DiseasesPrimary Sclerosing Cholangitis
University of Birmingham58 enrolled5 locationsNCT06286709
Recruiting
Phase 2Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
DermatomyositisIdiopathic Inflammatory Myopathy
Cabaletta Bio74 enrolled35 locationsNCT06154252
Recruiting
Phase 2
Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV
MicrobiomeHIVCannabis+3 more
University of California, San Diego90 enrolled1 locationNCT05514899
Recruiting
Phase 2
Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)
KSHV Inflammatory Cytokine Syndrome (KICS)Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease
National Cancer Institute (NCI)75 enrolled1 locationNCT06052618
Recruiting
Phase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
ColitisInflammatory Bowel DiseasesUlcerative Colitis
Spyre Therapeutics, Inc.645 enrolled175 locationsNCT07012395
Recruiting
Phase 2Phase 3
Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM)
Idiopathic Inflammatory Myositis (IIM)DERMATOMYOSITIS OR POLYMYOSITIS
Restem, LLC.40 enrolled2 locationsNCT07160205
Recruiting
Phase 2
IMVT-1402 in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Chronic Inflammatory Demyelinating Polyneuropathy
Immunovant Sciences GmbH162 enrolled135 locationsNCT07032662
Recruiting
Phase 2
A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Takeda36 enrolled20 locationsNCT06798012
Recruiting
Phase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Inflammatory Bowel DiseasesCrohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)385 enrolled215 locationsNCT06226883
Recruiting
Phase 2
Study of DISC-0974-201 in Participants With IBD and Anemia
AnemiaInflammatory Bowel Disease (IBD)Inflammatory Bowel Disease (IBD); Anemia
Disc Medicine, Inc21 enrolled8 locationsNCT07368972
Recruiting
Phase 2
Pentoxifylline in Patients With Ulcerative Colitis
Inflammatory Bowel Diseases
Ihab Elsayed Hassan60 enrolled1 locationNCT07349472
Recruiting
Phase 2Phase 3
Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Janssen Research & Development, LLC201 enrolled108 locationsNCT05327114
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Idiopathic Inflammatory MyopathiesSystemic Sclerosis
Nkarta, Inc.144 enrolled15 locationsNCT06733935
Recruiting
Phase 2Phase 3
Activation of Autophagy and Suppression of Apoptosis by Dapagliflozin Attenuates Inflammatory Bowel Disease
Inflammatory Bowel Diseases
Mostafa Bahaa50 enrolled1 locationNCT05986136
Recruiting
Phase 2
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
Crohn's DiseaseUlcerative Colitis (UC)Inflammatory Bowel Disease (IBD)
Mirador Therapeutics, Inc.140 enrolled66 locationsNCT07113522
Recruiting
Phase 2
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)
KSHV Inflammatory Cytokine Syndrome (KICS)KSHVHHV-8
National Cancer Institute (NCI)140 enrolled1 locationNCT01419561
Recruiting
Phase 2
Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis
Immune-related Adverse EventInflammatory Arthritis
Tom Appleton30 enrolled1 locationNCT06037811
Recruiting
Phase 2
Phase 2 Study of Rapcabtagene Autoleucel in Myositis
Idiopathic Inflammatory Myopathies
Novartis Pharmaceuticals123 enrolled55 locationsNCT06665256
Recruiting
Phase 2
IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 Antibodies
Small Fiber NeuropathyAutoimmune Small Fiber NeuropathyInflammatory Polyneuropathy+1 more
Endeavor Health20 enrolled1 locationNCT04153422
Recruiting
Phase 2
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Systemic Sclerosis (SSc)Refractory Rheumatoid Arthritis (RA)Idiopathic Inflammatory Myopathies (IIMs)
Artiva Biotherapeutics, Inc.90 enrolled26 locationsNCT06991114