Early Phase 1 Injury Clinical Trials
16 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–16 of 16 trials
Recruiting
Early Phase 1
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
PainBrain InjuryBrain Tumors+3 more
University of Virginia40 enrolled1 locationNCT06810336
Recruiting
Early Phase 1
Quadriceps Motor Unit Adaptation to Simulated Knee Injury
Muscle InhibitionKnee Injury Simulation
University of Central Florida45 enrolled1 locationNCT06999057
Recruiting
Early Phase 1
Stimulating After Recovery From Traumatic Brain Injury
TBI (Traumatic Brain Injury)
University of Minnesota30 enrolled1 locationNCT05327829
Recruiting
Early Phase 1
Post-Operative Biomarker-Guided Precision Medicine For Cardiovascular Risk Reduction
myocardial injury after noncardiac surgery
NYU Langone Health50 enrolled1 locationNCT06961630
Recruiting
Early Phase 1
MEP Up-conditioning to Target Corticospinal Plasticity
Spinal Cord InjuryTetraplegia/Tetraparesis
Medical University of South Carolina11 enrolled1 locationNCT06989905
Recruiting
Early Phase 1
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Neurological injuryStrokeHealthy Volunteers+3 more
Northwell Health64 enrolled1 locationNCT04755699
Recruiting
Early Phase 1
Ketamine in Severe Traumatic Brain Injury
Traumatic Brain InjuryTraumatic Encephalopathy
University of Texas Southwestern Medical Center10 enrolled2 locationsNCT06062628
Recruiting
Early Phase 1
Testosterone and Neural Function
Spinal Cord Injury
VA Office of Research and Development15 enrolled1 locationNCT06130449
Recruiting
Early Phase 1
Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System
Cervical Spinal Cord Injury
University Health Network, Toronto7 enrolled1 locationNCT07299734
Recruiting
Early Phase 1
Feasibility and Safety of Intranasally Administered Breast Milk in HIE
Neonatal EncephalopathyBrain InjuryHypoxic Ischemic Encephalopathy of Newborn+4 more
Semmelweis University10 enrolled1 locationNCT06747260
Recruiting
Early Phase 1
Improving Traumatic Brain Injury Rehab Care With Comm Health Services: a Research Project Within the TBI Model System
Traumatic Brain Injury
Virginia Commonwealth University126 enrolled1 locationNCT06188364
Recruiting
Early Phase 1
MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)
Post-traumatic OsteoarthritisACL InjuryMeniscus Tear
Austin V Stone30 enrolled1 locationNCT04572256
Recruiting
Early Phase 1
Spinal Cord Associative Plasticity Study
Cervical Spinal Cord InjuryCervical MyelopathyTetraplegia/Tetraparesis
Columbia University92 enrolled3 locationsNCT05163639
Recruiting
Early Phase 1
Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury
Spinal Cord InjurySpinal Cord InjuriesSpinal Cord Injury Cervical+1 more
University of Mississippi Medical Center16 enrolled2 locationsNCT06274021
Recruiting
Early Phase 1
BioSpine: multimodal rehabilitation for individuals with complete chronic spinal cord injury
traumatic complete chronic spinal cord injury
Griffith University8 enrolled1 locationACTRN12622001272785
Completed
Early Phase 1
An Open-label, Single Arm, Pilot Study of the Feasibility of Measuring the Effect of Intranasal Acetylcysteine on Neurometabolic Markers Using Proton Magnetic Resonance Spectroscopy
Mild Traumatic Brain Injury
Clinical Network Services (CNS) Pty Ltd9 enrolled1 locationACTRN12620000949987