Phase 4 Intervention Clinical Trials
14 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–14 of 14 trials
Recruiting
Phase 4
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Percutaneous Coronary InterventionPeripheral Endovascular Intervention
Duke University6,000 enrolled78 locationsNCT06909565
Recruiting
Phase 4
Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After Percutaneous Coronary Intervention (PROMOTE)
Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
J.P.S Henriques300 enrolled1 locationNCT06916520
Recruiting
Phase 4
Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy
Acute Coronary SyndromeMyocardial InfarctionCoronary Artery Disease+1 more
Duk-Woo Park, MD3,320 enrolled43 locationsNCT04416581
Recruiting
Phase 4
Anti-platelet Effect of Berberine in Patients After Percutaneous Coronary Intervention
Coronary Artery DiseasePercutaneous Coronary Intervention
Peking Union Medical College Hospital64 enrolled1 locationNCT03378934
Recruiting
Phase 4
Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)
Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
University of Florida40 enrolled1 locationNCT07025148
Recruiting
Phase 4
Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
ObesityWeight LossWeight Management+2 more
The Royal's Institute of Mental Health Research40 enrolled3 locationsNCT06809166
Recruiting
Phase 4
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
Atrial Fibrillation (AF)Percutaneous Coronary Intervention (PCI)Oral Anticoagulation+1 more
Insel Gruppe AG, University Hospital Bern3,010 enrolled15 locationsNCT05955365
Recruiting
Phase 4
A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT ReductioN of DecREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease
Coronary Artery DiseasePercutaneous Coronary InterventionNo-Reflow Phenomenon
Korea University Anam Hospital460 enrolled1 locationNCT05427786
Completed
Phase 4
Relationship of serological levels for death receptors (TNFR1, TRAIL -R2, FAS ) With early pancreatic ß cell Apoptosis and Follow up after DPP4 inhibitors treatment in Syrian type 2 diabetic and impaired fasting glucose patients
the research problem is to study serum apoptotic biomarkers and inflammatory mediators in naive drug prediabetes to determine whether drug intervention (DPP4inhibitors ) can slow down or reverse apoptosis of pancreatic beta cell in order to limit conversion prediabetes to T2DM .
rama ayash -Damascus university ,-pharmacy college88 enrolled1 locationACTRN12624001135505
Recruiting
Phase 4
Sequential MonotherApy of TicagrElor and Clopidogrel After Coronary Intervention
Acute Coronary SyndromePercutaneous Coronary Intervention
Second Affiliated Hospital, School of Medicine, Zhejiang University2,690 enrolled1 locationNCT04937699
Recruiting
Phase 4
Ticagrelor With Low-dose Versus Regular Aspirin in Patients With Acute Coronary Syndrome (ACS) at High-Risk for Ischemia After Percutaneous Coronary Intervention
Acute Coronary SyndromeInterventional Cardiology
Fu Wai Hospital, Beijing, China1,220 enrolled1 locationNCT04240834
Recruiting
Phase 4
NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI
Acute Coronary SyndromeCoronary Artery DiseasePercutaneous Coronary Intervention
China National Center for Cardiovascular Diseases3,944 enrolled1 locationNCT05638867
Not Yet Recruiting
Phase 4
Carotid Stenosis Management During the COVID-19 Era with Best Medical Intervention Alone (CASCOM Study)
Arterial disease complication preventionCarotid artery stentingMedical intervention+3 more
Monash University1,543 enrolled15 locationsACTRN12621001604897
Recruiting
Phase 4
Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI
Atrial FibrillationAcute Coronary SyndromeAntithrombotic Therapy+1 more
Medical University of Gdansk2,230 enrolled1 locationNCT04695106