LCH Clinical Trials

1 recruiting

About LCH Clinical Trials

Looking for clinical trials for LCH? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new LCH trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about LCH clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Phase 3

A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)

Molecular Mechanisms of Pharmacological ActionPeripheral Nervous System AgentsNeurotransmitter Agents+7 more
Merz Aesthetics GmbH300 enrolled26 locationsNCT07210463
Recruiting
Not Applicable

Modified LCH-III Regimen With or Without Luvometinib for Multisystem Pediatric Langerhans Cell Histiocytosis

Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital120 enrolled11 locationsNCT07431060
Recruiting
Not Applicable

Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Participate in a Weight Loss Program, Half Will Receive Bed Scales, and Participants Who Receive the Bed Scales Are Expected to Have Increased Weight Loss.

Disability PhysicalWheelchair
Jonathan Pearlman92 enrolled1 locationNCT07141342
Recruiting
Phase 4

Colchicine's Effect on Inflammatory Markers

ColchicineInflammation in Cardiac Surgery
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Not Applicable

Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions

Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital62 enrolled11 locationsNCT07371182
Recruiting
Phase 4

Pilot Trial of Colchicine for Graft Failure in CABG

Graft FailureCABGColchicine
Ruijin Hospital100 enrolled1 locationNCT06802926
Recruiting

Ilaris NIS in Korea

Systemic Juvenile Idiopathic Arthritis (sJIA)Hereditary Periodic Fever SyndromesCryopyrin-associated Periodic Syndromes (CAPS)+3 more
Novartis Pharmaceuticals25 enrolled1 locationNCT06838143
Recruiting
Phase 3

A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United States

Molecular Mechanisms of Pharmacological ActionPeripheral Nervous System AgentsNeurotransmitter Agents+7 more
Merz North America, Inc.300 enrolled28 locationsNCT07122193
Recruiting
Phase 2

Mirdametinib in Histiocytic Disorders

Histiocytic DisordersRosai-Dorfman Disease (RDD)Langerhans Cell Histiocytosis (LCH)+1 more
Children's Hospital Medical Center, Cincinnati40 enrolled1 locationNCT06153173
Recruiting
Phase 4

The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery

Atrial FibrillationCoronary Artery DiseaseCoronary Artery Bypass Grafting+1 more
Tomsk Cardiology Research Institute140 enrolled1 locationNCT06798714
Recruiting

Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic

Microvascular DysfunctionMicrovascular AnginaMINOCA+4 more
University Hospital, Motol1,000 enrolled1 locationNCT07103317
Recruiting
Not Applicable

Virtual Peer Coaching in Manual Wheelchair Skills

Spinal Cord InjurySpinal Cord Injuries (SCI)Tetraplegia/Tetraparesis+2 more
University of Pittsburgh132 enrolled1 locationNCT06295146
Recruiting
Not Applicable

Effect of Bempedoic Acid on Liver Fat in Individuals With Nonalcoholic Fatty Liver Disease and Type 2 Diabetes

Type 2 DiabetesNon Alcholic Fatty Liver Disease
Medanta, The Medicity, India100 enrolled1 locationNCT06035874
Recruiting
Phase 2

Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children

Langerhans Cell Histiocytosis (LCH)
West China Second University Hospital20 enrolled1 locationNCT07022834
Recruiting
Not Applicable

Cardiometabolic Health Intervention Using Movement-to-Music Exercise

Cardiometabolic Risk Factors in Adult Wheelchair Users
University of Alabama at Birmingham132 enrolled1 locationNCT05606432
Recruiting
Phase 1Phase 2

Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction

HFpEF - Heart Failure With Preserved Ejection FractionColchicine
I.M. Sechenov First Moscow State Medical University40 enrolled2 locationsNCT05637398
Recruiting
Phase 3

Efficacy and Safety of Colchicine After PCI

Coronary Heart DiseasePercutaneous Coronary InterventionColchicine
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology8,862 enrolled36 locationsNCT06472908
Recruiting
Phase 2

To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH

Langerhans Cell HistiocytosisLCH
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.56 enrolled11 locationsNCT05997602
Recruiting
Not Applicable

The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)

Heart ArrhythmiaKidney Failure, AcuteMyopathy; Drugs+4 more
4th Military Clinical Hospital with Polyclinic, Poland32 enrolled1 locationNCT06707532
Recruiting
Not Applicable

Treatment of ACuTe Coronary Syndromes With Low-dose colchICine

Acute Coronary SyndromeColchicineUnstable Angina+2 more
Beijing Anzhen Hospital6,574 enrolled1 locationNCT06215989