Phase 4 Leg Clinical Trials

19 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 119 of 19 trials

Recruiting
Phase 4

Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients

DiabetesFracture Lower LegFracture Fixation, Internal
Texas Tech University Health Sciences Center, El Paso40 enrolled3 locationsNCT07561541
Recruiting
Phase 4

COMS for Chronic Ulcers Treatment

Wound HealVenous Leg UlcerMagnetic Field Exposure
Sebastian Probst122 enrolled10 locationsNCT06528873
Recruiting
Phase 4

Mechanochemical Ablation Versus Ultrasound-Guided Foam Sclerotherapy of the Great Saphenous Vein

Varicose Veins of Lower LimbVaricose Veins of Leg With Long Saphenous Vein Distribution
Antonio Eduardo Zerati50 enrolled1 locationNCT07561320
Recruiting
Phase 4

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

Venous UlcerDiabetic Foot UlcerUlcer+6 more
BioLab Holdings50 enrolled1 locationNCT07364630
Recruiting
Phase 4

Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)

Vasoplegia
University of Alberta870 enrolled1 locationNCT05058612
Recruiting
Phase 4

A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL

Diabetic Foot Ulcer (DFU)Venous Leg Ulcer (VLU)
HealthTech Wound Care150 enrolled10 locationsNCT07172893
Recruiting
Phase 4

Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers

Venous Leg Ulcer (VLU)
AOTI Ltd.212 enrolled1 locationNCT06754735
Recruiting
Phase 4

Single Shot Exparel vs Catheters in Lower Extremity Trauma

FractureFracture Dislocation of Ankle JointFracture Leg+2 more
George Washington University90 enrolled1 locationNCT07221019
Recruiting
Phase 4

Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers

Diabetic Foot UlcerDiabetic FootFoot Ulcer, Diabetic+6 more
BioLab Holdings650 enrolled1 locationNCT07089602
Recruiting
Phase 4

Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery

Vasoplegic Syndrome of Cardiac Surgery
University of Sao Paulo350 enrolled1 locationNCT06934798
Recruiting
Phase 4

Evaluation of Clinical Impact of the Type of Cardioplegia Used in the Patient Undergoing Major Cardiac Surgery.

Cardiac SurgeryHeart ArrestCardioplegia
Lourdes Montero Cruces600 enrolled1 locationNCT06530641
Recruiting
Phase 4

Comparison of the Efficacy of Ultrasound Guided vs Non-guided Suprascapular Nerve Block Treatment in Stroke Patients

StrokeHemiplegia
Abant Izzet Baysal University50 enrolled1 locationNCT05260125
Recruiting
Phase 4

Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

Diabetic Foot UlcerDiabetic FootFoot Ulcer, Diabetic+6 more
Tiger Biosciences, LLC.340 enrolled1 locationNCT06826339
Recruiting
Phase 4

Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

venous leg ulcersVenous Leg Ulcer (VLU)Venous Leg+1 more
Kerecis Ltd.150 enrolled1 locationNCT06693570
Recruiting
Phase 4

Effectiveness and Safety of At-home Gait Rehabilitation Using Wearable Exoskeletal Robot

StrokeGait, HemiplegicGait, Spastic
Yonsei University16 enrolled1 locationNCT06543758
Recruiting
Phase 4

Topical Sevoflurane for Treatment of Chronic Leg Ulcers

Leg Ulcer
Charles University, Czech Republic50 enrolled1 locationNCT05303805
Terminated
Phase 4

An adaptive clinical trial of topical, anti-inflammatory dressings on pain in adults with venous leg ulcers: Pilot study

venous leg ulcers
Queensland University of Technology30 enrolled2 locationsACTRN12617001632381
Completed
Phase 3Phase 4

A prospective, randomised controlled trial of auto-titrating Continuous positive airway pressure treatment for Obstructive Sleep Apnoea after acute Quadriplegia

Acute tetraplegia
Institute for Breathing and Sleep150 enrolled2 locationsACTRN12605000799651
Terminated
Phase 3Phase 4

Daily Tenderwet dressings vs QID normal Saline compress as wound debridement agents

Chronic leg ulcers
Fremantle Hospital & Health Service60 enrolled1 locationACTRN12605000180617