Phase 1 Lesion Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1Phase 2
Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
Multiple Sclerosis (MS)Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+4 more
University of California, San Francisco74 enrolled1 locationNCT05359653
Recruiting
Phase 1
PET [89Zr]DFO-starPEG in Solid Tumors
Solid TumorSolid CarcinomaSoft Tissue Lesion
Robert Flavell, MD, PhD13 enrolled1 locationNCT06894745
Recruiting
Phase 1
NWRD09 for HPV-16 Related Cervical HSIL
High-grade Squamous Intraepithelial Lesion (HSIL)
Newish Biotech (Wuxi) Co., Ltd.9 enrolled1 locationNCT07047989
Recruiting
Phase 1Phase 2
Safety and Exploratory Efficacy of Transplantation Therapy Using PSA-NCAM(+) NPC in AIS-A Level of Sub-acute SCI
Spinal Cord Injury, AcuteSpinal Cord Injury at C4 Level With Complete LesionSpinal Cord Injury at C5-C7 Level With Complete Lesion
S.Biomedics Co., Ltd.5 enrolled2 locationsNCT04812431
Recruiting
Phase 1
Safety of Anal Curcumin
Anal High Grade Squamous Intraepithelial Lesion
Lisa Flowers48 enrolled2 locationsNCT06626230
Completed
Phase 1
A Phase 1, Open-label Study to Determine the Safety, Tolerability, and Pharmacokinetics of Multiple Subcutaneous Doses of Pentosan Polysulfate Sodium (PPS) in Healthy Adult Participants
Bone Marrow LesionKnee Osteoarthritis
Paradigm Biopharmaceuticals Pty Ltd24 enrolled1 locationACTRN12620000829910
Completed
Phase 1
A Randomized, double-blind, placebo-controlled, single-dose, dose escalation study in healthy participants to evaluate safety, tolerability and pharmacokinetics of intra-vaginal ABI-1968
Cervical high-grade squamous intraepithelial lesions (HSIL)
Clinical Network Services, Pty Ltd.40 enrolled1 locationACTRN12617000467336
Completed
Phase 1
Comparison of two drug thinning agents (unfractionated heparin and low-molecular weight heparin) for prevention of stroke after brain aneurysm treatment utilizing coils or stents
Intracranial LesionsIntracranial Aneurysm
Royal Brisbane and Women's Hospital75 enrolled1 locationACTRN12616001277437
Withdrawn
Phase 1
A Feasibility Study of Local Effects of Thermal Vapor Ablation of Operable Cancer Lesions in the Lung
Cancerous lung lesions
Uptake Medical Corporation10 enrolled2 locationsACTRN12615000287538