Phase 1 Leukemia, Acute Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Leukemia, Lymphocytic, AcuteBlood CancerMyeloid Leukemia, Acute+8 more
National Cancer Institute (NCI)86 enrolled1 locationNCT06904066
Recruiting
Phase 1Phase 2
Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias
Acute Lymphoblastic LeukemiaSmall Lymphocytic LymphomaLymphoblastic Lymphoma+4 more
National Cancer Institute (NCI)132 enrolled1 locationNCT06364423
Recruiting
Phase 1
A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies
Chronic Myeloid LeukemiaMyelodysplastic SyndromesClassical Hodgkin Lymphoma+5 more
MacroGenics130 enrolled7 locationsNCT05362773
Recruiting
Phase 1Phase 2
CD19-directed CAR-T Cell Therapy for R/R Acute Leukemia and Lymphoma
Lymphoma, Non-HodgkinLeukemia, Acute Lymphoblastic
University of Sao Paulo81 enrolled5 locationsNCT06101381
Recruiting
Phase 1
CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS
Myelodysplastic SyndromesLeukemia, Acute Lymphocytic (ALL)Leukemia, Acute Myelogenous (AML)
Zhujiang Hospital30 enrolled1 locationNCT03291444
Recruiting
Phase 1
CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia
CARRefractory LeukemiaLymphoblastic Leukemia in Children+4 more
National University Hospital, Singapore20 enrolled1 locationNCT05043571
Recruiting
Phase 1
ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia.
CARLymphoblastic Leukemia in ChildrenLymphoblastic Leukemia+3 more
National University Hospital, Singapore40 enrolled1 locationNCT05038696