lichen sclerosus Clinical Trials

10 recruitingLast updated: June 21, 2026

There are 10 actively recruiting lichen sclerosus clinical trials across 7 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Washington D.C., District of Columbia, United States, New York, New York, United States, Birmingham, Alabama, United States. Updated daily from ClinicalTrials.gov.


lichen sclerosus Trials at a Glance

10 actively recruiting trials for lichen sclerosus are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Washington D.C., New York, and Birmingham. Lead sponsors running lichen sclerosus studies include Clinica Dermatologica Arbache ltda, Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare, and Andrew T. Goldstein, MD.

Browse lichen sclerosus trials by phase

Treatments under study

About lichen sclerosus Clinical Trials

Looking for clinical trials for lichen sclerosus? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new lichen sclerosus trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about lichen sclerosus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Phase 3

A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus

lichen sclerosus
LEO Pharma652 enrolled7 locationsNCT07335588
Recruiting
Not Applicable

Laser Treatment for Lichen Sclerosus

Lichen Sclerosus Lesion
Sciton50 enrolled1 locationNCT06389071
Recruiting
Not Applicable

VALOR: Vaginal Atrophy & Long-term Observation of Recovery

Atrophic vaginitisGenitourinary Syndrome of MenopauseVaginal Atrophy+3 more
Stratpharma AG2,000 enrolled14 locationsNCT05953090
Recruiting

Male Lichen Sclerosus - Risk Factors, Treatment, and Impact on Quality of Life

lichen sclerosus
Region Västerbotten300 enrolled1 locationNCT06984263
Recruiting
Phase 2

Methotrexate for Severe Vulvar Lichen Sclerosus

vulvar lichen sclerosus
Clinica Dermatologica Arbache ltda12 enrolled1 locationNCT07352917
Recruiting
Not Applicable

Dynamic Quadripolar Radiofrequency VS Topical Corticosteroids in Women With Vulvar Lichen Sclerosus

vulvar lichen sclerosus
Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare68 enrolled1 locationNCT07363733
Recruiting
Not Applicable

To Compare Inflammatory Biomarkers Before and After Treatment With Clobetasol or Fractional CO2 Laser, in Women With Histologically Confirmed Vulvar Lichen Sclerosus, Without Prior Corticosteroid Treatment.

vulvar lichen sclerosus
Universidade Federal do Rio de Janeiro40 enrolled1 locationNCT07240519
Recruiting
Not Applicable

Comparison of Laser Treatment With Clobetasol Therapy in Patients With Lichen Sclerosus

lichen sclerosus
Kantonsspital Winterthur KSW120 enrolled1 locationNCT06135402
Recruiting
Phase 1

StrataMGT in the Reduction of Vulvar Lichen Sclerosus (LS) Symptoms

vulvar lichen sclerosus
Andrew T. Goldstein, MD100 enrolled3 locationsNCT06662942
Recruiting
Phase 1Phase 2

Use of Platelet Rich Plasma from Cord Blood Vs Placebo in the Treatment of Vulvar Lichen Sclerosus

vulvar lichen sclerosus
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico100 enrolled1 locationNCT06661382