Phase 1 LN Clinical Trials
24 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 24 trials
Recruiting
Phase 1
Dose Escalation Study With Bispecific Antibodies in Adult Patients With Lupus Nephritis
Lupus Nephritis (LN)
Regeneron Pharmaceuticals90 enrolled11 locationsNCT06975787
Recruiting
Phase 1
A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)
Lupus Nephritis (LN)Systemic Lupus Erthematosus (SLE)Extra-renal Lupus (ERL)
Hinge Bio30 enrolled1 locationNCT07491900
Recruiting
Phase 1Phase 2
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)
Beijing GoBroad Hospital18 enrolled1 locationNCT06585514
Recruiting
Phase 1
A Phase I Study of HY-2003 in the Subjects With Excessive Submental Fat Accumulation
Moderate or Severe Submental Fullness
Sichuan Huiyu Pharmaceutical Co., Ltd30 enrolled2 locationsNCT06756490
Recruiting
Phase 1Phase 2
PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia
Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled4 locationsNCT07101640
Recruiting
Phase 1
Intravenous DNase I for the Treatment of Sepsis (IDEALSepsisI)
SepsisCritical Illness
McMaster University36 enrolled1 locationNCT05453695
Recruiting
Phase 1
An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
Systemic Lupus ErythematosusLupus Nephritis (LN)Inflammatory Myopathy+3 more
China Immunotech (Beijing) Biotechnology Co., Ltd.18 enrolled1 locationNCT07236762
Recruiting
Phase 1
A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)Inflammatory Myopathy+3 more
China Immunotech (Beijing) Biotechnology Co., Ltd.18 enrolled1 locationNCT07104721
Recruiting
Phase 1
A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)Sjogren's Syndrome (SS)+3 more
China Immunotech (Beijing) Biotechnology Co., Ltd.18 enrolled1 locationNCT07123519
Recruiting
Phase 1Phase 2
Mindfulness Meditation for Insomnia
InsomniaMindfulnessTelemedicine+2 more
Brigham and Women's Hospital30 enrolled1 locationNCT06972303
Recruiting
Phase 1Phase 2
Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors
Advanced Solid Malignant Tumors (With Positive Expression of MSLN in Tumor Tissue)
Shenzhen University General Hospital20 enrolled1 locationNCT07399769
Recruiting
Phase 1
Intralesional Ronkyla Plus Injection for the Treatment of Superficial Lipoma
LipomaSubmental Fullness
Glonova Pharma Co., Ltd56 enrolled2 locationsNCT07237425
Recruiting
Phase 1Phase 2
Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial
Critical Illness
Wandercraft5 enrolled1 locationNCT07220733
Recruiting
Phase 1
Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder
MindfulnessGuanfacine
Rutgers, The State University of New Jersey224 enrolled1 locationNCT06642181
Recruiting
Phase 1
A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus
Lupus Nephritis (LN)Immune Thrombocytopenia (ITP)
China Immunotech (Beijing) Biotechnology Co., Ltd.36 enrolled1 locationNCT06943937
Recruiting
Phase 1Phase 2
Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 1
Slow Introduction of Nutrition for Ill Malnourished Children
Malnutrition, ChildMalnutrition, Severe AcuteMalnutrition, Infant
The Hospital for Sick Children135 enrolled2 locationsNCT06846749
Recruiting
Phase 1Phase 2
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Sexual DysfunctionAutoimmune DiseasesNeurologic Disorders+8 more
Thomas Advanced Medical LLC5,000 enrolled1 locationNCT04684602
Completed
Phase 1
A study to evaluate the prebiotic effect of Manuka Honey with Cyclopower (Trademark) capsules in healthy subjects.
Gastrointestinal effect and wellness
The New Zealand Institute for Plant and Food Research20 enrolled1 locationACTRN12615000857505
Completed
Phase 1
Nutrition supplementation and immunity in athletes
Upper respiratory tract illnessGastrointestinal illness
Australian Institute of Sport40 enrolled1 locationACTRN12611000771954