Lower Limb Amputation Above Knee Clinical Trials

10 recruitingLast updated: May 21, 2026

There are 10 actively recruiting lower limb amputation above knee clinical trials across 6 countries. Studies span Not Applicable. Top locations include Austin, Texas, United States, Chicago, Illinois, United States, Échirolles, France. Updated daily from ClinicalTrials.gov.


Lower Limb Amputation Above Knee Trials at a Glance

10 actively recruiting trials for lower limb amputation above knee are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Austin, Chicago, and Échirolles. Lead sponsors running lower limb amputation above knee studies include Hanger Institute for Clinical Research and Education, LLC, Liberating Technologies, Inc., and Campus Bio-Medico University.

Browse lower limb amputation above knee trials by phase

About Lower Limb Amputation Above Knee Clinical Trials

Looking for clinical trials for Lower Limb Amputation Above Knee? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Lower Limb Amputation Above Knee trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Lower Limb Amputation Above Knee clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

TENS for Restoring Somatotopic Sensory Feedback in Lower Limb Amputees and Improving Phantom Limb Perception

Lower Limb Amputation Below KneeLower Limb Amputation Above Knee
Campus Bio-Medico University15 enrolled1 locationNCT07448350
Recruiting
Not Applicable

Microenvironment in Patients Undergoing Non-traumatic Amputation

Lower Limb Amputation Above Knee
University of Aarhus20 enrolled1 locationNCT07384689
Recruiting
Not Applicable

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

AmputationLower Limb Amputation Above Knee (Injury)Limb; Absence, Congenital, Lower+3 more
Hanger Institute for Clinical Research and Education, LLC100 enrolled1 locationNCT06937242
Recruiting
Not Applicable

Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System

Lower Limb Amputation Below KneeLower Limb Amputation Above KneePhantom Limb Pain After Amputation+1 more
Median20 enrolled1 locationNCT07324109
Recruiting
Not Applicable

Prosthetic Performance Enhancement Trial

AmputationLower Limb Amputation Above Knee (Injury)Lower Limb Amputation Below Knee (Injury)+3 more
University of Nevada, Las Vegas35 enrolled1 locationNCT06419920
Recruiting
Not Applicable

Study on a Prosthetic Foot With Adjustable Heel Height

Lower Limb Amputation Below KneeLower Limb Amputation Above Knee
Otto Bock France SNC30 enrolled5 locationsNCT07214493
Recruiting
Not Applicable

Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees

AmputationLower Limb Amputation Above Knee (Injury)Amputation; Traumatic, Leg, Lower+3 more
Liberating Technologies, Inc.26 enrolled1 locationNCT06194838
Recruiting

Assessment of the Prosthetic System Impact on Mental Workload in Above-knee Lower Limb Amputees.

Lower Limb Amputation Above Knee (Injury)
Proteor Group9 enrolled1 locationNCT06635655
Recruiting

C-STAR Movement Database

StrokeParkinson DiseaseLower Limb Amputation Above Knee (Injury)+1 more
Shirley Ryan AbilityLab250 enrolled1 locationNCT05471375
Recruiting
Not Applicable

Self-Management for Amputee Rehabilitation Using Technology.

AmputationBehaviorLower Limb Amputation Above Knee (Injury)+2 more
University of British Columbia82 enrolled1 locationNCT04953364