Phase 3 Lung Disease Clinical Trials

16 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 116 of 16 trials

Recruiting
Phase 3

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.

Lung Diseases
Fundación GECP129 enrolled30 locationsNCT06431633
Recruiting
Phase 3

A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

Interstitial Lung DiseasesSystemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Boehringer Ingelheim400 enrolled158 locationsNCT06806592
Recruiting
Phase 3

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

Interstitial Lung DiseasesFamilial Pulmonary FibrosisInterstitial Lung Abnormalities
Boehringer Ingelheim80 enrolled56 locationsNCT07201922
Recruiting
Phase 3

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Progressive Pulmonary FibrosisInterstitial Lung Disease
United Therapeutics698 enrolled152 locationsNCT05943535
Recruiting
Phase 3

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Interstitial Lung DiseasePulmonary Hypertension
Insmed Incorporated344 enrolled68 locationsNCT07179380
Recruiting
Phase 3

Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease

Interstitial Lung DiseaseSystemic Sclerosis
National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland86 enrolled1 locationNCT06297096
Recruiting
Phase 3

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

Lung Diseases, Interstitial
GlaxoSmithKline440 enrolled131 locationsNCT06572384
Recruiting
Phase 2Phase 3

Anlotinib Capsules in the Treatment for IPF/PF-ILDs

Interstitial Lung Diseases
First Affiliated Hospital of Wenzhou Medical University30 enrolled1 locationNCT05828953
Recruiting
Phase 2Phase 3

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

Scleroderma, SystemicSystemic Sclerosis Associated Interstitial Lung Disease
GlaxoSmithKline300 enrolled131 locationsNCT05878717
Recruiting
Phase 3

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections

Lung InfectionMAC Lung Disease
Centre Hospitalier Universitaire, Amiens424 enrolled3 locationsNCT03236987
Recruiting
Phase 2Phase 3

Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases

Lung Diseases, Interstitial
R-Pharm International, LLC138 enrolled33 locationsNCT06440746
Recruiting
Phase 2Phase 3

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Qifangfeixian Granules in the Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

Interstitial Lung DiseaseQifangfeixian Granules
Huilan Zhang124 enrolled1 locationNCT06674148
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Rituximab in Patients With Progressive Interstitial Lung Disease (ILD) With Inflammatory Component: a Multicentre Double-blind Placebo-controlled Randomized Trial

Lung Diseases
University Hospital, Tours126 enrolled1 locationNCT05596786
Not Yet Recruiting
Phase 3

Effect of nebulised furosemide on breathlessness and cough in interstitial lung disease: a pilot study

Interstitial Lung Disease
Hunter New England Health12 enrolled1 locationACTRN12619001032145
Terminated
Phase 3

Opioids for breathlessness in people with mesothelioma or asbestosis or other causes of interstitial lung disease.

Dyspnoea in opioid naive participants with mesothelioma or asbestosis or other causes of interstitial lung disease.
Flinders University - Department of Palliative and Support Services144 enrolled3 locationsACTRN12611000711910
Completed
Phase 2Phase 3

Effect of N-acetylcysteine supplementation on oxidation status and alveolar inflammation in people exposed to asbestos: a double-blind randomised clinical trial

Asbestos related lung disease
University of Western Australia70 enrolled1 locationACTRN12609000818235