Phase 3 Lupus Erythematosus Clinical Trials
18 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–18 of 18 trials
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
UCB Biopharma SRL450 enrolled225 locationsNCT06617325
Recruiting
Phase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
Systemic Lupus Erythematosus (SLE)Cutaneous Lupus Erythematosus (CLE)
EMD Serono Research & Development Institute, Inc.202 enrolled3 locationsNCT07332481
Recruiting
Phase 3
A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment
Lupus Erythematosus, SystemicNephritis, Lupus
Viatris Innovation GmbH300 enrolled9 locationsNCT07201129
Recruiting
Phase 2Phase 3
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Subacute Cutaneous Lupus ErythematosusChronic Cutaneous Lupus Erythematosus
Biogen450 enrolled314 locationsNCT05531565
Recruiting
Phase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
Cutaneous Lupus ErythematosusSystematic Lupus Erythematosus
EMD Serono Research & Development Institute, Inc.202 enrolled3 locationsNCT07355218
Recruiting
Phase 3
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Janssen Research & Development, LLC600 enrolled27 locationsNCT07438496
Recruiting
Phase 3
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
Systemic Lupus Erythematosus
AstraZeneca100 enrolled97 locationsNCT05835310
Recruiting
Phase 3
A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Viatris Innovation GmbH420 enrolled216 locationsNCT05648500
Recruiting
Phase 3
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).
Systemic Lupus Erythematosus
Novartis Pharmaceuticals550 enrolled127 locationsNCT06133972
Recruiting
Phase 3
A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus
AstraZeneca302 enrolled272 locationsNCT06015737
Recruiting
Phase 3
Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
AbbVie1,000 enrolled369 locationsNCT05843643
Recruiting
Phase 3
Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
Systemic Lupus Erythematosus
NYU Langone Health330 enrolled10 locationsNCT05799378
Recruiting
Phase 3
Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF
Systemic Lupus Erythematosus (SLE)Lupus Nephritis
Assistance Publique - Hôpitaux de Paris196 enrolled1 locationNCT04702256
Recruiting
Phase 2Phase 3
Safety of Administering Isoniazid to SLE Patients to Prevent TB
TuberculosisSystemic Lupus Erythematosus
Universitas Padjadjaran60 enrolled1 locationNCT06618573
Recruiting
Phase 3
Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Liu Tian60 enrolled1 locationNCT05339217
Recruiting
Phase 3
A Study to Evaluate the Safety and Tolerability of Epratuzumab in Patients With Systemic Lupus Erythematosus.
Systemic Lupus Erythematosus
UCB Inc1,400 enrolled70 locationsACTRN12612000298819
Recruiting
Phase 3
Study of Epratuzumab versus Placebo in subjects with moderate to severe general Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus
UCB, Inc1,053 enrolled57 locationsACTRN12611000464965
Recruiting
Phase 3
A Study of Belimumab, a Fully Human Monoclonal Anit-BLyS Antibody, in Subjects With Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus (SLE)
Kendle R&D Pty Limited810 enrolled1 locationACTRN12607000327482