Early Phase 1 Malignancy Clinical Trials

6 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 16 of 6 trials

Recruiting
Early Phase 1

Universal CAR-T Cells (REVO-UWD-19) for Refractory and Relapsed B-Cell Tumors

B-cell LymphomaB-cell MalignancyB-Cell Leukemia
Wondercel Biotech (ShenZhen)30 enrolled1 locationNCT06662227
Recruiting
Early Phase 1

HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCT

Hematologic Malignancy
Duke University10 enrolled1 locationNCT06731504
Recruiting
Early Phase 1

A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in Adult Participants With Relapsed/Refractory CD19-positive B-cell Malignant Hematological Tumors

Hematological Malignancy (Leukemia- Lymphoma)
Grit Biotechnology34 enrolled1 locationNCT07131254
Recruiting
Early Phase 1

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Chronic Myeloid LeukemiaHodgkin LymphomaNon-Hodgkin Lymphoma+9 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1

Anti-CD19-CAR-T Cells in Subjects With Relapsed/Refractory B Cell Malignancies

B-cell Malignancy
Shanghai First Song Biotechnology Co., LTD9 enrolled1 locationNCT06532630
Recruiting
Early Phase 1

Safety, Tolerability and Preliminary Efficacy of Engineered Red Blood Cell in Patients With Advanced Malignancies

CancerSolid TumorHematologic Malignancy
Westlake Therapeutics30 enrolled1 locationNCT05707325