Malignant Solid Neoplasm Clinical Trials in Columbus, Ohio

21 recruitingColumbus, Ohio

Showing 120 of 21 trials

Recruiting
Phase 2

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Solid NeoplasmMalignant Female Reproductive System NeoplasmRecurrent Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI)70 enrolled185 locationsNCT06126276
Recruiting
Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Malignant Female Reproductive System Neoplasm+12 more
National Cancer Institute (NCI)2,900 enrolled479 locationsNCT05564377
Recruiting
Phase 1

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Metastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI)43 enrolled23 locationsNCT05687110
Recruiting
Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 2

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Metastatic Malignant Solid NeoplasmAdvanced Malignant Solid Neoplasm
National Cancer Institute (NCI)105 enrolled182 locationsNCT05638295
Recruiting
Phase 3

Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm
University of Rochester NCORP Research Base400 enrolled153 locationsNCT04829539
Recruiting
Phase 1

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+37 more
National Cancer Institute (NCI)51 enrolled23 locationsNCT04704661
Recruiting
Phase 2

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Metastatic Malignant Solid NeoplasmAdvanced Malignant Solid Neoplasm
National Cancer Institute (NCI)500 enrolled27 locationsNCT06311214
Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Head and Neck CarcinomaMalignant Solid NeoplasmSarcoma+59 more
Alliance for Clinical Trials in Oncology2,000 enrolled745 locationsNCT05334069
Recruiting
Not Applicable

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmMetastatic Malignant Neoplasm in the Spine
Ohio State University Comprehensive Cancer Center200 enrolled1 locationNCT05178472
Recruiting
Phase 3

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+7 more
NRG Oncology269 enrolled263 locationsNCT06500455
Recruiting
Not Applicable

Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

Malignant Solid Neoplasm
ECOG-ACRIN Cancer Research Group760 enrolled181 locationsNCT06295367
Recruiting
Phase 3

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

AnorexiaHematopoietic and Lymphoid Cell NeoplasmAdvanced Malignant Solid Neoplasm
Alliance for Clinical Trials in Oncology360 enrolled293 locationsNCT04939090
Recruiting

Project: Every Child for Younger Patients With Cancer

Malignant Solid NeoplasmNeuroendocrine NeoplasmCentral Nervous System Neoplasm+15 more
Children's Oncology Group75,000 enrolled278 locationsNCT02402244
Recruiting
Phase 3

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Children's Oncology Group60 enrolled187 locationsNCT06513962
Recruiting
Phase 2

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial

Hematopoietic and Lymphatic System NeoplasmAdvanced Malignant Solid Neoplasm
Yuanquan Yang40 enrolled1 locationNCT06470971
Recruiting
Phase 3

Comparing Radiation Therapy to Usual Care for Patients With High-Risk Bone Asymptomatic Metastases, PREEMPT Trial

Metastatic Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the Bone
NRG Oncology280 enrolled576 locationsNCT06745024
Recruiting
Not Applicable

Weighted Blanket Use to Reduce Anxiety in Oncology Patients

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm
Ohio State University Comprehensive Cancer Center114 enrolled1 locationNCT06089408
Recruiting
Not Applicable

Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial

Malignant Solid NeoplasmHematopoietic and Lymphoid System Neoplasm
Ohio State University Comprehensive Cancer Center208 enrolled1 locationNCT06314672
Recruiting
Not Applicable

Pre-Operative Guided Meditation to Reduce Pre-Operative Anxiety in Patients Undergoing Cancer-Directed Surgery

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Ohio State University Comprehensive Cancer Center200 enrolled1 locationNCT06949943