Microsatellite Instability Clinical Trials in Guangzhou, Guangdong
5 recruitingGuangzhou, Guangdong, China
Showing 1–5 of 5 trials
Recruiting
Phase 1
AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors
Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)
Amgen464 enrolled21 locationsNCT07403721
Recruiting
Phase 1Phase 2
Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer
Colorectal Cancer Stage IVMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)
Sun Yat-sen University28 enrolled1 locationNCT05426005
Recruiting
Phase 2
Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal Cancer
Colorectal, CancerMismatch Repair DeficiencyMicrosatellite Instability High
Sun Yat-sen University105 enrolled1 locationNCT06903858
Recruiting
Phase 2
Neoadjuvant Toripalimab With or Without Celecoxib in dMMR/MSI-H Colorectal Cancer
Colorectal, CancerNeoadjuvant TherapyMismatch Repair-deficient (dMMR)+1 more
Sun Yat-sen University270 enrolled1 locationNCT03926338
Recruiting
Phase 3
Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer
Colorectal, CancerMicrosatellite Instability High
Sun Yat-sen University180 enrolled1 locationNCT06520683