Phase 1 NAD Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
Metastatic Hepatocellular CarcinomaLocal Advanced Hepatocellular CarcinomaAlpha-fetoprotein (AFP)-Producing Gastric Cancer+2 more
BeOne Medicines392 enrolled29 locationsNCT06427941
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of 5 mg bis [(E)-7-[4-(4-fluorophenyl)- 6-isopropyl-2- [methyl(methylsulfonyl) amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt orally disintegrated tablet (ODT) against the innovator 40 mg bis [(E)-7-[4-(4-fluorophenyl)- 6-isopropyl-2- [methyl(methylsulfonyl) amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt oral tablet conducted under fasting conditions in healthy volunteers.
bis [(E)-7-[4-(4-fluorophenyl)- 6-isopropyl-2- [methyl(methylsulfonyl) amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt is indicated in patients with no hyperchloesterolaemia as an adjunct to diet when the response to diet and exercise is inadequate.
Zenith Technology Corporation Limited16 enrolled1 locationACTRN12621001409864
Not Yet Recruiting
Phase 1
Testosterone to treat men with mild to moderate Crohn's disease
Crohn's DiseaseHypogonadal
Fiona Stanley Hospital46 enrolled2 locationsACTRN12620000338965
Completed
Phase 1
Topical estradiol add-back in hypogonadal men: dose-finding study
Prostate CancerHypogonadism
University of Melbourne36 enrolled2 locationsACTRN12616000373471
Completed
Phase 1
A pharmacokinetic study to assess the effect of two different formulations of Testosterone Metered Dose (MD) Lotion on the pharmacokinetics of testosterone in hypogonadism
Hypogonadism
Acrux DDS Pty Ltd12 enrolled1 locationACTRN12605000528651
Completed
Phase 1
A pharmacokinetic phase I study to assess the effect of different application sites on the pharmacokinetics of testosterone from a Testosterone Metered Dose (MD) Lotion in hypogonadism.
Hypogonadism
Acrux DDS Pty Ltd12 enrolled1 locationACTRN12605000518662
Completed
Phase 1
A randomised, two-way crossover study to compare the pharmacokinetics of testosterone following application of a Testosterone Metered Dose (MD) lotion or AndroGel in men with low serum testosterone
Hypogonadism
Acrux DDS Pty Ltd6 enrolled1 locationACTRN12605000517673