Phase 1 Neonatal Clinical Trials

6 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–6 of 6 trials

Recruiting

Phase 1

Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Staphylococcus AureusMicrobial ColonizationNeonatal Infection

Johns Hopkins University175 enrolled1 locationNCT06283355

Recruiting

Phase 1

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

Genetic epilepsyDevelopmental and Epileptic EncephalopathiesEpileptic Spasms+1 more

Heather Olson10 enrolled1 locationNCT06700811

Recruiting

Phase 1

Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation

Cardiac Arrest Neonatal

University of Alberta20 enrolled1 locationNCT05738148

Not Yet Recruiting

Phase 1

A First in Human, Randomized, Double-Blind, Placebo-Controlled, Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of TT20 Administered Intravenously as Single Dose Infusions and Continuous Infusions in Healthy Adult Volunteers

Neonatal Brain Injury

Tellus Therapeutics72 enrolled1 locationACTRN12625000892415

Recruiting

Phase 1Phase 2

Neonatal Hypoxic Ischemic Encephalopathy : Safety and Feasibility Study of a Curative Treatment With Autologous Cord Blood Stem Cells

neonatal hypoxic ischaemic encephalopathy

Assistance Publique Hopitaux De Marseille20 enrolled1 locationNCT02881970

Withdrawn

Phase 1

NEOSTeM (NEOnatal STroke Mesenchymal Stem Cell) Trial: Assessing the Safety of Mesenchymal Stem Cells for Babies with Stroke

Term/near term neonatal stroke

Sydney Children's Hospital Network12 enrolled2 locationsACTRN12624000145505