Phase 1 NET Clinical Trials
47 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 47 trials
Recruiting
Phase 1
Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
Solid TumorLymphomaGIST+5 more
ITM Solucin GmbH20 enrolled5 locationsNCT06441331
Recruiting
Phase 1
Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose
Healthy ParticipantsPharmacokinetics
Amgen400 enrolled5 locationsNCT07422285
Recruiting
Phase 1
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
NeoplasmsNeoplasms by SiteBrain Diseases+30 more
M.D. Anderson Cancer Center24 enrolled3 locationsNCT03911388
Recruiting
Phase 1
Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon
Breast ReconstructionGenetic PredispositionPerfusion; Complications+1 more
Duke University25 enrolled1 locationNCT07264790
Recruiting
Phase 1
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725
Netherton Syndrome
BioCryst Pharmaceuticals78 enrolled12 locationsNCT06539507
Recruiting
Phase 1
Pharmacokinetics of Sulopenem Etzadroxil Plus Probenecid in Adolescents
Pharmacokinetics After Oral Intake
Iterum Therapeutics, International Limited12 enrolled1 locationNCT07092813
Recruiting
Phase 1
Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102)
Pharmacokinetics
Ensysce Biosciences30 enrolled1 locationNCT06500793
Recruiting
Phase 1
A Study to Assess Sulbactam-durlobactam in Pediatric Patients With Acinetobacter Baumannii-calcoaceticus Complex Infection
Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)
Innoviva Specialty Therapeutics48 enrolled4 locationsNCT06801223
Not Yet Recruiting
Phase 1
A study to assess the safety of increasing single doses of AP003 in healthy adults.
Liver-associated inborn errors of metabolismArg-TGA premature termination codon mutationsLiver stop codon disease+1 more
Alltrna, Incorporated30 enrolled1 locationACTRN12626000194369
Recruiting
Phase 1
Acute Effects of Oral Nicotine Pouches
Nicotine Pouch Self-AdministrationNicotine Pharmacokinetic StudyNicotine Pharmacodynamic Study
Johns Hopkins University120 enrolled1 locationNCT07128329
Recruiting
Phase 1
Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome
Netherton Syndrome
Azitra Inc.12 enrolled2 locationsNCT06137157
Recruiting
Phase 1
A Phase 1 Ethnobridging TriaL of AGA2118 in Healthy Japanese, Chinese, and Caucasian ParticipantS (ATLAS)
Healthy ParticipantsPharmacokinetic Study
Angitia Incorporated Limited30 enrolled1 locationNCT07361354
Recruiting
Phase 1
Pharmacokinetics of Olverembatinib in Participants With Hepatic Impairment
PharmacokineticOlverembatinib
Ascentage Pharma Group Inc.48 enrolled1 locationNCT07282093
Recruiting
Phase 1
Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination
Healthy VolunteerSafetyPharmacokinetics+2 more
Basilea Pharmaceutica46 enrolled1 locationNCT06733675
Recruiting
Phase 1Phase 2
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+13 more
Tanabe Pharma America, Inc.27 enrolled6 locationsNCT06943521
Recruiting
Phase 1
Study of BB-025, Alone and After BB-031, in Healthy Volunteers
Healthy VolunteersPharmacokineticsPharmacodynamics
Basking Biosciences, Inc.72 enrolled1 locationNCT07202663
Recruiting
Phase 1
Safety, Tolerability, and Pharmacokinetics of RCS-21 in Healthy Volunteers.
SafetyHealthy VolunteersTolerability+1 more
RNATICS GmbH24 enrolled1 locationNCT06752122
Recruiting
Phase 1
High Potency Cannabis: Acute and Protracted Effects
PainPharmacokineticsAbuse Cannabis
University of California, Los Angeles30 enrolled1 locationNCT06859723
Recruiting
Phase 1Phase 2
Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors
Safety IssuesTolerabilityPharmacokinetics
Nanjing Immunophage Biotech Co., Ltd196 enrolled7 locationsNCT05142592
Recruiting
Phase 1
Food Effect on PK of DW-1021 (Pelubiprofen 45 mg / Tramadol 45.9 mg) in Healthy Adults
Healthy VolunteersPharmacokineticsFood Effect in Healthy Volunteers
Haiphong University of Medicine and Pharmacy14 enrolled2 locationsNCT07060209