Phase 1 NET Clinical Trials

57 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 120 of 57 trials

Recruiting
Phase 1

Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

Solid TumorNeuroendocrine TumorsGep Net+6 more
RayzeBio, Inc.104 enrolled9 locationsNCT07165132
Recruiting
Phase 1

A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725

Netherton Syndrome
BioCryst Pharmaceuticals78 enrolled12 locationsNCT06539507
Recruiting
Phase 1Phase 2

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

ParagangliomaPheochromocytomaSolid Tumor Cancer+19 more
Fundación de investigación HM25 enrolled1 locationNCT06607692
Recruiting
Phase 1Phase 2

Study of EPI-001 in Patients With Androgenetic Alopecia

androgenetic alopecia
Epibiotech42 enrolled1 locationNCT07618195
Recruiting
Phase 1

Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102)

Healthy VolunteerPharmacokinetics
Ensysce Biosciences54 enrolled1 locationNCT06500793
Recruiting
Phase 1Phase 2

Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Healthy Adults With and Without Androgenetic Alopecia

Androgenetic alopecia (AGA)Healthy Volunteers - Male and Female
Absci Pty Ltd.227 enrolled4 locationsNCT07317544
Recruiting
Phase 1

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NeoplasmsNeoplasms by SiteBrain Diseases+30 more
M.D. Anderson Cancer Center24 enrolled3 locationsNCT03911388
Recruiting
Phase 1Phase 2

Opioid Drug Interaction Study

Drug Kineticsdrug interactions
Shanna Babalonis, PhD25 enrolled1 locationNCT06757140
Recruiting
Phase 1Phase 2

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

Colorectal, CancerStenosisFibrosis, Liver+4 more
Massachusetts General Hospital80 enrolled1 locationNCT05692024
Recruiting
Phase 1

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

Solid TumorLymphomaGIST+5 more
ITM Solucin GmbH20 enrolled5 locationsNCT06441331
Recruiting
Phase 1

Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose

Healthy ParticipantsPharmacokinetics
Amgen400 enrolled5 locationsNCT07422285
Recruiting
Phase 1

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

Breast ReconstructionGenetic PredispositionPerfusion; Complications+1 more
Duke University25 enrolled1 locationNCT07264790
Recruiting
Phase 1

Pharmacokinetics of Sulopenem Etzadroxil Plus Probenecid in Adolescents

Pharmacokinetics After Oral Intake
Iterum Therapeutics, International Limited12 enrolled1 locationNCT07092813
Recruiting
Phase 1Phase 2

A Study to Evaluate Safety and Efficacy of OLX72021 in Healthy Males With Androgenetic Alopecia

Androgenetic alopecia (AGA)
Olix Pharmaceuticals, Inc.158 enrolled1 locationNCT07327359
Recruiting
Phase 1

A Study to Assess Sulbactam-durlobactam in Pediatric Patients With Acinetobacter Baumannii-calcoaceticus Complex Infection

Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)
Innoviva Specialty Therapeutics48 enrolled4 locationsNCT06801223
Recruiting
Phase 1Phase 2

Secretome vs. PRP Injections for Hair Density and Growth in Androgenetic Alopecia Patients

androgenetic alopecia
PT. Prodia Stem Cell Indonesia40 enrolled1 locationNCT07429253
Not Yet Recruiting
Phase 1

A study to assess the safety of increasing single doses of AP003 in healthy adults.

Liver-associated inborn errors of metabolismArg-TGA premature termination codon mutationsLiver stop codon disease+1 more
Alltrna, Incorporated30 enrolled1 locationACTRN12626000194369
Recruiting
Phase 1

Acute Effects of Oral Nicotine Pouches

Nicotine Pouch Self-AdministrationNicotine Pharmacokinetic StudyNicotine Pharmacodynamic Study
Johns Hopkins University120 enrolled1 locationNCT07128329
Recruiting
Phase 1

Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome

Netherton Syndrome
Azitra Inc.12 enrolled2 locationsNCT06137157
Recruiting
Phase 1

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

Genetic epilepsyDevelopmental and Epileptic EncephalopathiesEpileptic Spasms+1 more
Heather Olson10 enrolled1 locationNCT06700811