Phase 1 Neuropathic Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1Phase 2
Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study
Diabetic NeuropathiesDiabetic Peripheral Neuropathic Pain (DPN)
Florida A&M University20 enrolled1 locationNCT07298408
Recruiting
Phase 1Phase 2
Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)
Chronic Neuropathic Pain
Sangamo Therapeutics27 enrolled11 locationsNCT06980948
Recruiting
Phase 1
A Study of HRS-2129 in Patients With Diabetic Peripheral Neuropathic Pain
Diabetic peripheral neuropathic pain
Shandong Suncadia Medicine Co., Ltd.168 enrolled2 locationsNCT07377721
Recruiting
Phase 1
Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
Spinal StenosisDegenerative Disc DiseaseSpinal Cord Injuries+2 more
EicOsis Human Health Inc.36 enrolled1 locationNCT06438471
Recruiting
Phase 1Phase 2
(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain
Pain, Neuropathic
Rush University Medical Center25 enrolled1 locationNCT05864053
Recruiting
Phase 1
MAD Study to Assess the Safety, Tolerability, PKs and Efficacy of YJ001 for Spray Use in Patients With DPNP
Diabetic peripheral neuropathic pain
Zhejiang Hanmai Pharmaceutical Technology Co., Ltd.24 enrolled1 locationNCT06361108
Recruiting
Phase 1Phase 2
Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI
Neuropathic PainSCI - Spinal Cord Injury
University of Miami20 enrolled1 locationNCT05630235
Recruiting
Phase 1
Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers
Diabetes MellitusDiabetic Foot UlcerDiabetic Foot+8 more
University of the Punjab28 enrolled1 locationNCT05610865
Recruiting
Phase 1
A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.
Post-herpetic neuralgiaPainChronic Pain+4 more
iN Therapeutics Co., Ltd.64 enrolled1 locationNCT06218784
Completed
Phase 1
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of STC-004
Chronic, peripheral neuropathic pain
SiteOne Therapeutics76 enrolled1 locationACTRN12624000642583
Completed
Phase 1
Study of ZYN001 (transdermal patch) in Healthy Volunteers
Peripheral neuropathic painFibromyalgia
Zynerba Pharmaceuticals Pty. Ltd20 enrolled1 locationACTRN12617001028392
Completed
Phase 1
A Phase 1, Randomised, Open-Label, Three-way Crossover Comparative Pharmacokinetic Study of Capsule and Tablet Dosage Forms of EMA401 Sodium Salt When Administered Orally in Healthy Adult Males
Neuropathic Pain
Spinifex Pharmaceuticals Pty Ltd15 enrolled1 locationACTRN12615000074594
Completed
Phase 1
A Phase 1, Adaptive, Single and Multiple Ascending Dose Study of EMA401 Sodium Salt Administered Orally in Healthy, Adult Males to Determine the Maximum Tolerated Dose and Pharmacokinetic Profiles
Neuropathic Pain
Spinifex Pharmaceuticals Pty Ltd84 enrolled1 locationACTRN12614000802606