Phase 1 Newly Diagnosed Multiple Myeloma Clinical Trials

5 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 15 of 5 trials

Recruiting
Phase 1

Safety and Efficacy of RN1201 Injection as First-Line Treatment for Newly Diagnosed Multiple Myeloma

Newly Diagnosed Multiple Myeloma (NDMM)Multiple Myloma
The First Affiliated Hospital of Soochow University18 enrolled1 locationNCT07652138
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of 10 mg 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione capsule against the innovator 10 mg 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione capsule conducted under fasting conditions in healthy male volunteers.

3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione is indicated for the treatment of patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation.
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12619001501134
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 25 mg capsule against the innovator 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 25 mg capsule conducted under fasting conditions in healthy male volunteers.

3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione is indicated for the treatment of patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation.
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12619001492145
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione capsule against the innovator 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione capsule conducted under fasting conditions in healthy male volunteers.

3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione is indicated for the treatment of patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation.
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12619001352190
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione capsule against the innovator 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione capsule conducted under fasting conditions in healthy male volunteers.

4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is indicated for the treatment of patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplantation.
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12619001338156