Phase 2 Pelvis Clinical Trials

10 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 110 of 10 trials

Recruiting
Phase 2Phase 3

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Muscle Invasive Bladder Urothelial CarcinomaStage IV Bladder Urothelial Carcinoma AJCC v7Muscle Invasive Renal Pelvis Urothelial Carcinoma+4 more
National Cancer Institute (NCI)992 enrolled494 locationsNCT05987241
Recruiting
Phase 2

Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers

Stage IV Bladder Cancer AJCC v7Metastatic Bladder Urothelial CarcinomaMetastatic Renal Pelvis and Ureter Urothelial Carcinoma+3 more
Mayo Clinic70 enrolled1 locationNCT07087860
Recruiting
Phase 2Phase 3

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Renal Pelvis and Ureter Urothelial Carcinoma
National Cancer Institute (NCI)249 enrolled258 locationsNCT04628767
Recruiting
Phase 2

An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma

NeoplasmsClear Cell Renal Cell CarcinomaMalignant Neoplasms+1 more
Yonsei University78 enrolled1 locationNCT07469683
Recruiting
Phase 2

Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer

Renal Pelvis and Ureter Urothelial Carcinoma
Jonsson Comprehensive Cancer Center21 enrolled1 locationNCT05775471
Recruiting
Phase 1Phase 2

Sacituzumab Govitecan Plus EV in Metastatic UC

Metastatic Urothelial CarcinomaUrothelial CancerBladder Cancer+1 more
Dana-Farber Cancer Institute106 enrolled1 locationNCT04724018
Recruiting
Phase 2Phase 3

Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma

Urothelial Carcinoma of the Renal Pelvis and UreterTransitional Cell Cancer of the Renal Pelvis and Ureter
University of British Columbia70 enrolled4 locationsNCT06124976
Recruiting
Phase 2

Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial Carcinoma

Urothelial Carcinoma BladderUrothelial Carcinoma of the Renal Pelvis and UreterUrothelial Carcinoma Urethra+1 more
Nagoya University43 enrolled1 locationNCT06983210
Recruiting
Phase 2

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

Bladder AdenocarcinomaBladder Squamous Cell CarcinomaMetastatic Bladder Carcinoma+8 more
Emory University25 enrolled4 locationsNCT05756569
Recruiting
Phase 2

9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma

Urothelial CarcinomaUrothelial Carcinoma BladderUrothelial Carcinoma of the Renal Pelvis and Ureter+1 more
Mabwell (Shanghai) Bioscience Co., Ltd.60 enrolled2 locationsNCT06823427