Phase 1 PET Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1

Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)

Intestinal FloraIrritable Bowel SyndromeProbiotic+3 more
The First Affiliated Hospital of Soochow University400 enrolled1 locationNCT06960369
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of 2-(diethylamino-N-(2,6-dimethylphenyl)acetamide 5% w/w trandermal patch against the innovator 32-(diethylamino-N-(2,6-dimethylphenyl)acetamide 5% w/w trandermal patch conducted under fasting conditions in healthy male and female volunteers.

2-(diethylamino-N-(2,6-dimethylphenyl)acetamide is used as a local anaesthetic. It is indicated for symptomatic relief of nerve pain associated with medically diagnosed post-herpetic neuralgia (post-shingles pain).
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12622000141741
Completed
Phase 1

An investigation into the effect of skin stimulation on smell function

DementiaParkinson's DiseaseAppetite disorders
Yusuf Ozgur Cakmak48 enrolled1 locationACTRN12617000034336
Completed
Phase 1

A Phase I, Open-Label, Twice Daily Dose, Pharmacokinetic Study of EMA401 Sodium Salt Administered Orally in Healthy Elderly Subjects

Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd8 enrolled1 locationACTRN12610000961044
Completed
Phase 1

A Phase I, Randomised, Open-Label, Three-way Crossover Comparative Pharmacokinetic Study of EMA401 Sodium Salt When Administered Orally in Fed (high fat meal or orange juice only) and Fasted Healthy Adult Males.

Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd15 enrolled1 locationACTRN12610000798066
Completed
Phase 1

A Phase I Multiple Ascending Dose Study of EMA401 Sodium Salt Administered Orally in Healthy Elderly Subjects

Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd32 enrolled1 locationACTRN12610000620022
Completed
Phase 1

A phase I, randomised, double-blind, placebo controlled, dose ranging study to evaluate the safety, tolerability and pharmacokinetics of EMA401 following multiple oral dosing in healthy male subjects.

Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd36 enrolled1 locationACTRN12609000489291
Completed
Phase 1

A Phase I, Randomized, Double-Blind, Placebo-Controlled Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of EMA401 Following Single Ascending Oral Dosing of EMA401.Na in Healthy Volunteers Administered Orally in the Fasted and Fed State.

Postherpetic Neuralgia
Spinifex Pharmaceuticals Pty Ltd.36 enrolled1 locationACTRN12608000335392