Phase 1 PME Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1Phase 2
Gene Replacement Therapy for Treatment of Paediatric Patients With CTNNB1 Neurodevelopmental Syndrome
CTNNB1 Neurodevelopmental Syndrome
CTNNB1 Foundation12 enrolled1 locationNCT07270549
Recruiting
Phase 1
Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies
Developmental and Epileptic EncephalopathiesEpileptic Spasms
Heather Olson10 enrolled1 locationNCT06700811
Recruiting
Phase 1
Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
Cannabis UseChild Development
University of Colorado, Denver140 enrolled1 locationNCT06379971
Completed
Phase 1
An Open-label, 2 Part, Study to Assess the Pharmacokinetics of a Spray Dried Dispersion Formulation of Radiprodil Under Fasted and Fed Conditions in Healthy Adult Subjects: Part B
Glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
GRIN Therapeutics, Inc.18 enrolled1 locationACTRN12624001440516
Completed
Phase 1
An Open-label, 2 Part, Study to Assess the Pharmacokinetics of a Spray Dried Dispersion Formulation of Radiprodil Under Fasted and Fed Conditions in Healthy Adult Subjects: Part A
Glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
GRIN Therapeutics, Inc.18 enrolled1 locationACTRN12624001366549
Completed
Phase 1
A Phase 1 Study to Evaluate the Effect of Multiple Doses of Rabeprazole on the Pharmacokinetics of a Single Dose of Radiprodil in Healthy Adult Participants
Malformations of Cortical Development
GRIN Therapeutics, Inc.18 enrolled1 locationACTRN12624000878572