Phase 3 Polyp Clinical Trials
15 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–15 of 15 trials
Recruiting
Phase 3
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Sanofi210 enrolled121 locationsNCT06834347
Recruiting
Phase 3
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Sanofi210 enrolled113 locationsNCT06834360
Recruiting
Phase 3
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
Chronic Rhinosinusitis With Nasal Polyps
AstraZeneca180 enrolled45 locationsNCT06706817
Recruiting
Phase 3
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Eli Lilly and Company510 enrolled194 locationsNCT06338995
Recruiting
Phase 3
Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps
Chronic Rhinosinusitis Without Nasal Polyps
Optinose US Inc.84 enrolled21 locationsNCT06850805
Recruiting
Phase 3
OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps
Bilateral Nasal Polyposis
Optinose US Inc.72 enrolled40 locationsNCT03747458
Recruiting
Phase 3
Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy
Myocardial Infarction (MI)Cardiovascular EventsPost Polypectomy Bleeding in Antiplatelet Patients
Chinese University of Hong Kong2,514 enrolled1 locationNCT07052799
Recruiting
Phase 3
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled26 locationsNCT06950385
Recruiting
Phase 3
Efficacy and Durability of a Personalized Treat-and-extend Regimen of Faricimab for Treatment-naive Polypoidal Choroidal Vasculopathy
Polypoidal Choroidal Vasculopathy (PCV)
Yeungnam University College of Medicine50 enrolled1 locationNCT07461441
Recruiting
Phase 3
Prospective Trial of the Efficacy and Safety of a Personalized Regimen of High-dose Aflibercept 8mg on Treatment-naive Polypoidal Choroidal Vasculopathy: the PALLAS Trial
Polypoidal Choroidal VasculopathyPolypoidal Choroidal Vasculopathy (PCV)
Yeungnam University College of Medicine50 enrolled1 locationNCT07389980
Recruiting
Phase 3
Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.246 enrolled60 locationsNCT07107256
Recruiting
Phase 3
Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Guangdong Hengrui Pharmaceutical Co., Ltd280 enrolled1 locationNCT07132827
Recruiting
Phase 2Phase 3
Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS).
Chronic Rhinosinusitis With Nasal PolypsChronic Rhinosinusitis Without Nasal Polyps
Region Skane50 enrolled1 locationNCT07184684
Recruiting
Phase 3
Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis
Yonsei University28 enrolled1 locationNCT06545526
Completed
Phase 3
A randomised, double blinded trial of Succinylated Gelatin versus normal saline for submucosal injection for colonic endoscopic mucosal resection (EMR)
Sessile polyps of the colon
Dr Alan Moss and Dr Michael Bourke160 enrolled1 locationACTRN12609000939291