Post-Treatment Lyme Disease Clinical Trials

9 recruitingLast updated: May 29, 2026

There are 9 actively recruiting post-treatment lyme disease clinical trials across 1 country. Studies span Not Applicable, Phase 1, Phase 2, Early Phase 1. Top locations include New York, New York, United States, Washington D.C., District of Columbia, United States, Delafield, Wisconsin, United States. Updated daily from ClinicalTrials.gov.


Post-Treatment Lyme Disease Trials at a Glance

9 actively recruiting trials for post-treatment lyme disease are listed on ClinicalTrialsFinder across 6 cities. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in New York, Washington D.C., and Delafield. Lead sponsors running post-treatment lyme disease studies include Children's National Research Institute, Columbia University, and Icahn School of Medicine at Mount Sinai.

Browse post-treatment lyme disease trials by phase

Treatments under study

About Post-Treatment Lyme Disease Clinical Trials

Looking for clinical trials for Post-Treatment Lyme Disease? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Post-Treatment Lyme Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Post-Treatment Lyme Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Not Applicable

Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain

Chronic PainPost-treatment Lyme Disease Syndrome
Icahn School of Medicine at Mount Sinai20 enrolled1 locationNCT06655844
Recruiting
Not Applicable

taVNS for Persistent Symptoms From Lyme Disease

Post-Treatment Lyme Disease
Columbia University24 enrolled1 locationNCT05776251
Recruiting
Not Applicable

Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

Post-Treatment Lyme Disease
Columbia University110 enrolled2 locationsNCT06915324
Recruiting
Phase 1Phase 2

Ceftriaxone for Post-Treatment Lyme Disease

Post-treatment Lyme Disease Syndrome
Hackensack Meridian Health20 enrolled1 locationNCT06785402
Recruiting
Early Phase 1

Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease

Post-Treatment Lyme Disease
State University of New York - Upstate Medical University44 enrolled1 locationNCT06611111
Recruiting
Phase 1Phase 2

Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Myalgic EncephalomyelitisChronic Fatigue SyndromePost-treatment Lyme Disease Syndrome+1 more
Icahn School of Medicine at Mount Sinai120 enrolled1 locationNCT06511050
Recruiting

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Traumatic Brain InjuryEhlers-Danlos SyndromePost-Acute COVID-19 Syndrome+41 more
Brain Inflammation Collaborative10,000 enrolled1 locationNCT04806620
Recruiting

Navigating Pregnancy and Parenthood With Lyme Disease

Lyme DiseaseChronic Lyme DiseasePregnancy Complications+4 more
Children's National Research Institute30 enrolled1 locationNCT06397794
Recruiting

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

Lyme DiseaseChronic Lyme DiseasePregnancy Complications+3 more
Children's National Research Institute40 enrolled1 locationNCT06026969