Phase 2 PREM Clinical Trials

26 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 26 trials

Recruiting
Phase 2

Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer

Breast CancerHER2-negative Breast CancerHormone Receptor Positive Tumor+1 more
SOLTI Breast Cancer Research Group96 enrolled15 locationsNCT05982093
Recruiting
Phase 2

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting
Phase 2

Co-administration of Acetaminophen With Ibuprofen to Improve Duct-Related Outcomes in Extremely Premature Infants

Patent Ductus Arteriosus After Premature Birth
Mount Sinai Hospital, Canada310 enrolled9 locationsNCT05340582
Recruiting
Phase 1Phase 2

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled4 locationsNCT07101640
Recruiting
Phase 2

Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions

Premalignant Lesion
M.D. Anderson Cancer Center45 enrolled1 locationNCT06561087
Recruiting
Phase 2

Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Reported Outcomes, and Safety in Men With Lifelong Premature Ejaculation (LPE)

Premature Ejaculation
Kadence Bio40 enrolled1 locationNCT07434271
Recruiting
Phase 2

Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants

Iron-deficiencyPrematurity
University of Washington120 enrolled1 locationNCT05340465
Recruiting
Phase 2

Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy

EsophagogastroduodenoscopySimethiconeN-Acetylcysteine+7 more
Hospital General de Mexicali132 enrolled2 locationsNCT07245095
Recruiting
Phase 2

Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation

Premature (Early) Ejaculation
Bioprojet60 enrolled1 locationNCT07047404
Recruiting
Phase 1Phase 2

Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency

Premature Ovarian Insufficiency
Yan Hongli50 enrolled1 locationNCT07115082
Recruiting
Phase 2Phase 3

Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress

Respiratory DiseaseVentilator Lung; NewbornPrematurity
Ministry of Health, Saudi Arabia134 enrolled2 locationsNCT06026163
Recruiting
Phase 1Phase 2

Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants

Infant, Premature, DiseasesCirculatory and Respiratory Physiological Phenomena
Instituto de Investigación Hospital Universitario La Paz30 enrolled3 locationsNCT06878742
Recruiting
Phase 2

PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study

Premenopausal HR+/HER2- Metastatic Breast Cancer
Samsung Medical Center178 enrolled1 locationNCT04819243
Recruiting
Phase 2Phase 3

Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients

Menopause Related ConditionsPremature Ovarian FailureMenopause, Premature+2 more
Genesis Athens Clinic100 enrolled1 locationNCT04031456
Recruiting
Phase 2

Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity

Retinopathy of Prematurity
University of Zurich276 enrolled3 locationsNCT03083431
Recruiting
Phase 2Phase 3

Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Retinopathy of Prematurity
Asociación para Evitar la Ceguera en México1 locationNCT00346814
Recruiting
Phase 2

Immunotherapy, Hormone Therapy, and AKT Inhibitor for Premenopausal ER Positive MBC

Metastatic Breast CancerER Positive Breast CancerPremenopausal Breast Cancer
National Taiwan University Hospital42 enrolled1 locationNCT05720260
Recruiting
Phase 2

Doxapram for Apnoea of Prematurity (DoxAPrem) Dosage Study

Apnoea of prematurity
University of Auckland32 enrolled1 locationACTRN12621001163897
Recruiting
Phase 2

Younger Women's Wellness Program for Premenstrual Syndrome in University students

Premenstrual Syndrome
Griffith University60 enrolled1 locationACTRN12620000996965
Recruiting
Phase 2

Randomized controlled trial (RCT) comparing between High versus Standard dose caffeine citrate for apnoea in prematurity

Apnoea of prematurity
Hospital Universiti Sains Malaysia78 enrolled1 locationACTRN12619001708145