Phase 2 PREM Clinical Trials
30 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 30 trials
Recruiting
Phase 2
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
Intraventricular hemorrhageChronic lung disease of prematurityBronchopulmonary Dysplasia+1 more
OHB Neonatology Ltd.338 enrolled72 locationsNCT03253263
Recruiting
Phase 1Phase 2
PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia
Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled5 locationsNCT07101640
Recruiting
Phase 2
Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants
Iron-Deficiency AnemiaIron-deficiencyPrematurity+1 more
University of Washington120 enrolled1 locationNCT05340465
Recruiting
Phase 2
Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity
Retinopathy of Prematurity
University of Zurich276 enrolled3 locationsNCT03083431
Recruiting
Phase 2
Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer
Breast CancerHER2-negative Breast CancerHormone Receptor Positive Tumor+1 more
SOLTI Breast Cancer Research Group96 enrolled15 locationsNCT05982093
Recruiting
Phase 2
The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD
Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting
Phase 2
Co-administration of Acetaminophen With Ibuprofen to Improve Duct-Related Outcomes in Extremely Premature Infants
Patent Ductus Arteriosus After Premature Birth
Mount Sinai Hospital, Canada310 enrolled9 locationsNCT05340582
Recruiting
Phase 2
Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions
Premalignant Lesion
M.D. Anderson Cancer Center45 enrolled1 locationNCT06561087
Recruiting
Phase 2
Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Reported Outcomes, and Safety in Men With Lifelong Premature Ejaculation (LPE)
Premature Ejaculation
Kadence Bio40 enrolled1 locationNCT07434271
Recruiting
Phase 1Phase 2
PK/PD of Digoxin in Infants With SVHD
Single VentricleInfant ConditionsInfant, Newborn, Diseases+1 more
Duke University20 enrolled2 locationsNCT06613477
Recruiting
Phase 2
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
EsophagogastroduodenoscopySimethiconeN-Acetylcysteine+7 more
Hospital General de Mexicali132 enrolled2 locationsNCT07245095
Recruiting
Phase 2
Anakinra Pilot 2 - A Study to Optimise Dose and Route of Administration of Anakinra in Preterm Infants
Very premature infantsPremature infantsInflammation
Monash Medical Centre24 enrolled2 locationsNCT07254000
Recruiting
Phase 2
Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation
Premature (Early) Ejaculation
Bioprojet60 enrolled1 locationNCT07047404
Recruiting
Phase 1Phase 2
Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency
Premature Ovarian Insufficiency
Yan Hongli50 enrolled1 locationNCT07115082
Recruiting
Phase 2Phase 3
Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress
Respiratory DiseaseVentilator Lung; NewbornPrematurity
Ministry of Health, Saudi Arabia134 enrolled2 locationsNCT06026163
Recruiting
Phase 2
Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients
Triple-Negative Breast CancerPremenopausal Breast Cancer
National Taiwan University Hospital124 enrolled1 locationNCT06225284
Recruiting
Phase 1Phase 2
Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants
Infant, Premature, DiseasesCirculatory and Respiratory Physiological Phenomena
Instituto de Investigación Hospital Universitario La Paz30 enrolled3 locationsNCT06878742
Recruiting
Phase 2
PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study
Premenopausal HR+/HER2- Metastatic Breast Cancer
Samsung Medical Center178 enrolled1 locationNCT04819243
Recruiting
Phase 2Phase 3
Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients
Menopause Related ConditionsPremature Ovarian FailureMenopause, Premature+2 more
Genesis Athens Clinic100 enrolled1 locationNCT04031456
Recruiting
Phase 2Phase 3
Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome
Retinopathy of Prematurity
Asociación para Evitar la Ceguera en México1 locationNCT00346814