Phase 4 PREM Clinical Trials
22 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 22 trials
Recruiting
Phase 4
Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women
EstrogenPremenopause
University of Delaware30 enrolled1 locationNCT06745466
Recruiting
Phase 4
Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress Syndrome
SurfactantRespiratory Distress Syndrome in Premature InfantsRespiratory Distress Syndrome (RDS)
Uludag University234 enrolled5 locationsNCT07350018
Recruiting
Phase 4
I.V Papavrine for Labor Induction in Term PROM
Premature Rupture of Membranes
Western Galilee Hospital-Nahariya110 enrolled1 locationNCT07517796
Recruiting
Phase 4
Pragmatic Evaluation of Respiratory Distress Syndrome Treatment in Africa
Premature BirthRespiratory Distress Syndrome in Premature InfantSurfactant Deficiency Syndrome Neonatal+1 more
Indiana University1,512 enrolled8 locationsNCT06554522
Recruiting
Phase 4
Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
Pregnancy, High RiskPreterm BirthPreterm Premature Rupture of Membrane
Ohio State University56 enrolled2 locationsNCT06396078
Recruiting
Phase 4
Single Dose of Antenatal Corticosteroids for Pregnancies at Risk of Preterm Delivery (SNACS)
Pregnancy ComplicationsPremature BirthObstetric Labor, Premature+2 more
McMaster University3,254 enrolled25 locationsNCT05114096
Recruiting
Phase 4
Azithromycin and Ampicillin for Late PPROM
Premature BirthAntibiotic ProphylaxisPrematurity+3 more
Sheba Medical Center311 enrolled1 locationNCT07183462
Recruiting
Phase 4
Prophylactic Minimally Invasive Surfactant Evaluation
Premature BirthRespiratory Distress Syndrome, Newborn
Endeavor Health200 enrolled1 locationNCT06007547
Recruiting
Phase 4
Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
Premature Ventricular Contraction (PVC)
Weill Medical College of Cornell University100 enrolled1 locationNCT03218137
Recruiting
Phase 4
Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD)
Johns Hopkins University288 enrolled2 locationsNCT06704594
Recruiting
Phase 4
OFS in Premenopausal Node+ Breast Cancer With Low Genomic Risk
Breast CancerNode-positive Breast CancerHER2-negative Breast Cancer+2 more
Gangnam Severance Hospital418 enrolled2 locationsNCT05333328
Recruiting
Phase 4
Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
Premature BirthPregnancy PretermPregnancy Prom+3 more
University Hospitals Cleveland Medical Center88 enrolled3 locationsNCT05345457
Recruiting
Phase 4
Safety and Efficacy of 18 mm Short Vitrectomy Probe for Pediatric Vitreoretinal Surgeries
Retinal DiseaseRetinal Vascular DisorderRetinopathy of Prematurity Both Eyes+6 more
Chang Gung Memorial Hospital60 enrolled1 locationNCT06520410
Recruiting
Phase 4
The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate
Apnea of PrematurityRespiratory FailurePremature Birth
Semmelweis University226 enrolled2 locationsNCT06401083
Not Yet Recruiting
Phase 4
Can Caffeine prevent the cessation of breathing in preterm newborn babies?
Apnea of PrematurityLow Birth WeightPrematurity
Mansoor Aslamzai130 enrolled1 locationACTRN12621001000897
Recruiting
Phase 4
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
Preterm LaborPreterm BirthRupture of Membranes; Delayed Delivery (Following Spontaneous Rupture)+3 more
Woman's34 enrolled1 locationNCT04047849
Completed
Phase 4
The Little Eye Drop Study: a randomised controlled non-inferiority trial on the microdrop administration of phenylephrine and cyclopentolate eye drops in neonates
Retinopathy of Prematurity
University of Otago150 enrolled5 locationsACTRN12619000795190
Completed
Phase 4
Preterm Paediatric Inhaled Corticosteroid Intervention (PICSI)
Chronic lung disease of prematurity
Telethon Kids Institute250 enrolled1 locationACTRN12618000781246
Not Yet Recruiting
Phase 4
SMOFLipid vs Clinoleic - randomised controlled trial
Patent ductus arteriosisPremature birth- Intra-ventricular haemorrhageParenteral nutrition associated cholestasis and liver disease
Nepean Hospital NICU44 enrolled1 locationACTRN12617000883314
Recruiting
Phase 4
Comparison of the incidence and duration of hypoglycaemia assessed by Continuous Glucose Monitoring (CGM) in elderly type 2 Diabetes patients treated with two different insulin regimens (long and short acting insulin VS premixed insulin) .
Type two Diabetes MellitusHypoglycaemia in elderly type two Diabetes Mellitus patients on premixed insulin treatment
Western Sydney Local Health District84 enrolled2 locationsACTRN12616001158459