Phase 1 Recurrent or Metastatic Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–7 of 7 trials

Recruiting

Phase 1

A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors

Recurrent or Metastatic Solid Tumors

Daiichi Sankyo76 enrolled26 locationsNCT07015697

Recruiting

Phase 1Phase 2

Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers

HPV 16+ Recurrent or Metastatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins24 enrolled1 locationNCT04713046

Recruiting

Phase 1Phase 2

A Study of YL201 in Combination With Toripalimab and With or Without Cisplatin in Nasopharyngeal Carcinoma.

Recurrent or Metastatic Nasopharyngeal Carcinoma

MediLink Therapeutics (Suzhou) Co., Ltd.202 enrolled20 locationsNCT07258979

Recruiting

Phase 1

Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors

Cervical CancerHNSCCHPV 16+ Recurrent or Metastatic Cancer

Therorna12 enrolled1 locationNCT07081984

Recruiting

Phase 1Phase 2

SHR-A1811 Combination Regimen for the Treatment of Recurrent or Metastatic Cervical Cancer

Recurrent or Metastatic Cervical Cancer

Suzhou Suncadia Biopharmaceuticals Co., Ltd.100 enrolled1 locationNCT06859775

Recruiting

Phase 1

Phase I Clinical Study of MBS301 in Treatment of HER2 Positive Recurrent or Metastatic Malignant Solid Tumor

HER2-positive Recurrent or Metastatic Malignant Solid Tumor

Beijing Mabworks Biotech Co., Ltd.34 enrolled1 locationNCT03842085

Recruiting

Phase 1

A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SSGJ-705 Monotherapy in Patients with Advanced Malignant Tumors

Locally Advanced, Recurrent or Metastatic Malignancies

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.180 enrolled1 locationNCT06390774