Phase 1 Rejection Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1
Treatment of Antibody-Mediated Rejection (ABMR) With CarBel
Kidney Transplant Rejection
National Institute of Allergy and Infectious Diseases (NIAID)25 enrolled10 locationsNCT06918990
Recruiting
Phase 1Phase 2
Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor
Kidney TransplantToleranceRenal Transplant Rejection
Jeffrey Veale, MD15 enrolled1 locationNCT03707262
Recruiting
Phase 1
Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in Solid Organ Transplant Recipients
Solid Organ Transplant ComplicationsSolid Organ Transplant RecipientsSolid Organ Transplant Rejection
Francisco Hernández Oliveros10 enrolled1 locationNCT06997471
Recruiting
Phase 1
A Phase 1 Clinical Trial of Siltuximab for the Treatment of Antibody-Mediated Rejection After Lung Transplantation
Antibody Mediated Rejection of Lung Transplant
Washington University School of Medicine30 enrolled2 locationsNCT06990711
Recruiting
Phase 1
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
Chronic Kidney DiseasesEnd-stage Kidney DiseaseKidney Transplant Failure and Rejection+1 more
University of California, Los Angeles10 enrolled1 locationNCT05525507
Recruiting
Phase 1Phase 2
CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk
Kidney FailureEnd Stage Renal DiseaseKidney Tumor+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053462
Recruiting
Phase 1Phase 2
CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection
Liver CancerLiver MetastasesLiver Cirrhosis+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053488
Recruiting
Phase 1Phase 2
Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant
Prevention of Rejection in Kidney Transplant
Eledon Pharmaceuticals48 enrolled9 locationsNCT05027906
Recruiting
Phase 1
Safety of Endobronchial Mesenchymal Stromal Cells in the Treatment of Chronic Lung Allograft Dysfunction
Chronic Lung DiseaseLung Transplant Rejection
Instituto De Investigación Sanitaria Puerta De Hierro-Segovia De Arana12 enrolled1 locationNCT06514378
Recruiting
Phase 1
Safety of DNP007 in Healthy Subjects
Liver Transplant; ComplicationsSteatohepatitis, NonalcoholicLiver Transplant Rejection
Seoul National University Hospital12 enrolled1 locationNCT06400771
Completed
Phase 1
A Randomized, Single-Dose and Multiple Dose Dose-Ranging Safety and Pharmacokinetics Study of Tacrolimus Powder for Inhalation in Healthy Adult Subjects
Prophylactic therapy of organ rejection in patients receiving allogeneic lung transplants
TFF Pharmaceuticals Australia Pty Limited64 enrolled2 locationsACTRN12620000192987