Phase 4 Risk Clinical Trials
28 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 28 trials
Recruiting
Phase 4
LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery
myocardial injury after non-cardiac surgeryAutonomic DysfunctionCardiovascular (CV) Risk+3 more
Insel Gruppe AG, University Hospital Bern114 enrolled1 locationNCT07168421
Recruiting
Phase 4
Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)
Type 1 DiabetesPregnancy, High Risk
Ohio State University44 enrolled1 locationNCT07293715
Recruiting
Phase 4
Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia
Perioperative Respiratory Adverse EventsHigh-RiskRespiratory Hypersensitivity+2 more
Sun Yat-sen University204 enrolled2 locationsNCT06624696
Recruiting
Phase 4
Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults
ObesityCardiometabolic Risk FactorsWeight Reduction
Asian Institute Of Medical Sciences60 enrolled1 locationNCT07513168
Recruiting
Phase 4
Blood Donor CVD 5000
Risk Reduction
University of Maryland, Baltimore150 enrolled1 locationNCT03971669
Recruiting
Phase 4
A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)
Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III)Human Papillomavirus (HPV) InfectionsHigh-risk HPV+1 more
Miquel Angel Pavon Ribas69 enrolled1 locationNCT05334706
Recruiting
Phase 4
Multi-center Randomized Controlled Clinical Study of Shenling Baishu Granule to Prevent the Recurrence of Low-risk Colorectal Adenoma
Low-risk Colorectal Adenoma
Shanghai Jiao Tong University School of Medicine624 enrolled1 locationNCT06930157
Recruiting
Phase 4
Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
Pregnancy, High RiskPreterm BirthPreterm Premature Rupture of Membrane
Ohio State University56 enrolled2 locationsNCT06396078
Recruiting
Phase 4
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
Pregnancy, High RiskGestational Diabetes Mellitus
Ohio State University1,572 enrolled21 locationsNCT06445946
Recruiting
Phase 4
Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs)
Non Muscle Invasive Bladder CancerHigh Risk Non-Muscle Invasive Bladder Urothelial CarcinomaNon-Muscle Invasive Bladder Urothelial Carcinoma
University of Roma La Sapienza327 enrolled1 locationNCT05962541
Recruiting
Phase 4
DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis
Cardiometabolic Risk FactorsCirrhosisCirrhotic Cardiomyopathy+1 more
Post Graduate Institute of Medical Education and Research, Chandigarh400 enrolled1 locationNCT07322237
Recruiting
Phase 4
Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >70 Years: the SCOPE-70 RCT Study
Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease
Yonsei University724 enrolled1 locationNCT03770312
Recruiting
Phase 4
Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)
Pregnancy, High RiskAnticoagulants
University of California, Irvine12 enrolled1 locationNCT04861103
Recruiting
Phase 4
Non-antithrombotic Versus. Single Antiplatelet Therapy Following Left Atrial Appendage Closure
Left Atrial Appendage ClosureAspirinNonvalvular Atrial Fibrillation+2 more
OCEAN-SHD Study Group500 enrolled21 locationsNCT07125417
Recruiting
Phase 4
Treatment of High-risk Newly Diagnosed Multiple Myeloma With Minimal Residual Disease Detection
MRDMultiple MyelomaHigh-Risk+1 more
The First Affiliated Hospital of Soochow University59 enrolled1 locationNCT06409702
Recruiting
Phase 4
Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes
Blood PressureDiabetes Mellitus, Type 2Adverse Event+2 more
XueQing Yu11,414 enrolled1 locationNCT03264352
Recruiting
Phase 4
The Efficacy and Safety of Non-vItamiN K antaGonist oraL Anticoagulants for intermEdiate Stroke Risk in Patients With Atrial Fibrillation (SINGLE-AF)
Atrial Fibrillation Patients With Intermediate Stroke Risk
Yonsei University1,800 enrolled1 locationNCT04437654
Recruiting
Phase 4
AnticoaguLation ONE Year After Ablation of Atrial Fibrillation in Patients With Atrial Fibrillation (ALONE AF Study)
Atrial Fibrillation Patients With Moderate or High Stroke Risk Who Had Undergone Catheter Ablation of Atrial Fibrillation
Yonsei University840 enrolled1 locationNCT04432220
Recruiting
Phase 4
Study investigating whether the drug semaglutide could be a safe and effective way of reducing metabolic problems, such as a high Body Mass Index (BMI) and high blood sugar levels, in people with psychosis.
Metabolic riskPsychosis
South Eastern Sydney Local Health District100 enrolled1 locationACTRN12621001434886
Completed
Phase 4
A study to compare 2 methods of inserting a pulmonary artery catheter in high risk cardiac surgical patients.
Severe left ventricular systolic dysfunctionMitral valve disease with severe pulmonary hypertensionHigh risk cardiac surgical patients+1 more
Austin Hopsital50 enrolled1 locationACTRN12614001081606