Phase 2 RNA Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 2

A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis

Moderate to Severe Vernal Keratoconjunctivitis
Laboratoires Thea120 enrolled11 locationsNCT07169695
Recruiting
Phase 2Phase 3

PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

ObesityCardiovascular DiseasesHypertension+3 more
University of Alabama at Birmingham160 enrolled1 locationNCT04971720
Recruiting
Phase 2

Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML

Acute Myeloid LeukemiaIntermediate Risk Acute Myeloid LeukemiaFLT3 Internal Tandem Duplication Positive+1 more
First Affiliated Hospital of Zhejiang University25 enrolled1 locationNCT07259707
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine

Herpes ZostermRNA Vaccine
Sinovac Biotech Co., Ltd519 enrolled1 locationNCT07400003
Recruiting
Phase 2

Induction Chemotherapy Combined With Tislelizumab for Locally Advanced Squamous Cell Carcinoma of the External Auditory Canal

Squamous Cell Carcinoma of External Auditory CanalLocally Advanced Tumor
Eye & ENT Hospital of Fudan University50 enrolled1 locationNCT07370337
Recruiting
Phase 2

Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer.

Refractory Germ Cell TumorsDornase Alfa
National Cancer Institute, Slovakia33 enrolled1 locationNCT07121322
Recruiting
Phase 2

A Phase II Study Evaluating the Efficacy and Safety of XH-S003 Capsules in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH - Paroxysmal Nocturnal Hemoglobinuria
S-INFINITY Pharmaceuticals Co., Ltd24 enrolled1 locationNCT06978699
Recruiting
Phase 2

Oxygen As an Acute Treatment in Alternating Hemiplegia of Childhood

Alternating Hemiplegia of Childhood
Assistance Publique - Hôpitaux de Paris24 enrolled2 locationsNCT06248645
Recruiting
Phase 2

Early Versus Conventional Cessation of Hydrocortisone in Septic Shock

Muscle WeaknessSeptic ShockHyperglycemia+4 more
Mahidol University160 enrolled1 locationNCT05818826
Completed
Phase 2

In vivo assessment of triple agent thermo-responsive otic gels in patients with acute otitis externa. Phase 2 trial.

Otitis Externa
University of Queensland30 enrolled1 locationACTRN12618001896268
Terminated
Phase 2

Low dose of oral corticosteroids in the treatment of painful acute otitis externa (swimmer's ear)

Acute otitis externa
James Cook University250 enrolled1 locationACTRN12615000059561
Not Yet Recruiting
Phase 2

A Trial of Polyethylene Glycol (PEG) Hydrogel to Reduce Rectal Radiation Dose During Radiotherapy for Prostate Cancer

Rectal toxicity during prostate radiotherapy (brachytherapy and/or external beam radiotherapy)
St George Hospital Cancer Care Centre40 enrolled1 locationACTRN12612000524897
Not Yet Recruiting
Phase 2

A Phase 2, Randomized, Double-Blinded, Vehicle-Controlled, Multicenter Study of Topical AS101 for External Genital Warts

External Genital Warts
Miramar Therapeutics, Inc, USA140 enrolled1 locationACTRN12607000580471
Completed
Phase 2Phase 3

Providing parents in a neonatal intensive care unit with audiorecordings of their conversation with neonatologists: a randomised trial.

2) Maternal depression, anxiety, general health and parenting stress scales.1) Poor recall by mothers of information given by neonatologists.
Dr Andrew Johnson, The Townsville Hospital200 enrolled1 locationACTRN12606000478516
Completed
Phase 2

A phase-II study of a modified Hyper-CVAD frontline therapy for patients with poor prognosis diffuse large B-cell and peripheral T-cell non-Hodgkins lymphoma to evaluate safety and improve remission rate.

Histologically aggressive non-Hodgkins lymphomaB- or T-cell lineage with a poor prognosis (International Prognostic Factors Index score of 2 or greater).
Australasian Leukaemia and Lymphoma Group70 enrolled1 locationACTRN12605000105640