Phase 1 Scar Clinical Trials

6 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–6 of 6 trials

Recruiting

Phase 1Phase 2

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency

Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseUrea Cycle Disorders, Inborn+1 more

iECURE, Inc.20 enrolled12 locationsNCT06255782

Recruiting

Phase 1

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars

Corneal Scar

Claris Biotherapeutics, Inc.20 enrolled7 locationsNCT06257355

Not Yet Recruiting

Phase 1

An Integrated Phase 1a/1b, First-in-human, Randomized, Double-blinded, Placebo-controlled Split-scar Study in a Cohort of Adult Participants with Hypertrophic Sternotomy Scars to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics

Hypertrophic Sternotomy Scars

Syntara Limited20 enrolled3 locationsACTRN12625001285448

Recruiting

Phase 1Phase 2

Halting Ornithine Transcarbamylase Deficiency With Recombinant AAV in ChildrEn

Ornithine Transcarbamylase Deficiency

University College, London12 enrolled1 locationNCT05092685

Completed

Phase 1

Comparative assessment of the absorption of a generic formulation of tiotropium test product 1 and tiotropium test product 2 against the innovator Spiriva HandiHaler conducted under fasting conditions in healthy male and female volunteers

Bioavailability study conducted in healthy volunteers comparing three formulations of tiotropium with no health condition or problem studied. Tiotropium is a long-acting, antimuscarinic agent, which is often referred to as an anticholinergic and is used to make breathing easier for people with Chronic Obstructive Pulmonary Disease (COPD).

Zenith Technology Corp Ltd24 enrolled1 locationACTRN12615000073505

Completed

Phase 1

A Phase I study to assess the safety of three formulations of the dermal implant ELAPR

The dermal implant ELAPR is being developed to treat the symptoms of skin aging or damage including wrinkles, scarring and photoaging.Healthy subjects are to be used in the study to assess the safety of the dermal implant.

Elastagen Pty Ltd12 enrolled1 locationACTRN12610000871044