Stage III Colon Cancer Clinical Trials

3 recruiting

Stage III Colon Cancer Trials at a Glance

7 actively recruiting trials for stage iii colon cancer are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Phase 2 with 4 trials, with the heaviest enrollment activity in New York, Columbus, and Atlanta. Lead sponsors running stage iii colon cancer studies include Emory University, Baylor College of Medicine, and Massachusetts General Hospital.

Browse stage iii colon cancer trials by phase

Treatments under study

About Stage III Colon Cancer Clinical Trials

Looking for clinical trials for Stage III Colon Cancer? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Stage III Colon Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Stage III Colon Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Phase 3

Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer

Metastatic Colon CancerStage III Colon Cancer
Massachusetts General Hospital400 enrolled3 locationsNCT03803553
Recruiting
Phase 2Phase 3

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Stage III Colon Cancer
NRG Oncology1,912 enrolled1054 locationsNCT05174169
Recruiting
Phase 2

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

Colorectal CarcinomaStage I Colorectal Cancer AJCC v8Stage II Colorectal Cancer AJCC v8+9 more
Emory University38 enrolled4 locationsNCT07405476
Recruiting
Phase 1

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+37 more
National Cancer Institute (NCI)51 enrolled23 locationsNCT04704661
Recruiting
Not Applicable

Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers

Stage III Colon Cancer AJCC v8Stage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8+3 more
Ohio State University Comprehensive Cancer Center70 enrolled1 locationNCT06746012
Recruiting
Phase 2

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

Stage III Colon Cancer AJCC v8Localized Colon CarcinomaStage IIB Colon Cancer AJCC v8+1 more
Emory University40 enrolled5 locationsNCT07140679
Recruiting
Phase 2

Phase II Open-label Trial of Neoadjuvant Immunochemotherapy for Resectable Non-metastatic Colon cancER: NICER

Stage I Colon CancerStage II Colon CancerStage III Colon Cancer
Baylor College of Medicine28 enrolled1 locationNCT05870800