Phase 4 Stage IV Clinical Trials

5 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 1–5 of 5 trials

Recruiting

Phase 4

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hepatocellular CarcinomaMetastatic Lung Non-Small Cell Carcinoma+18 more

OHSU Knight Cancer Institute160 enrolled1 locationNCT07405086

Recruiting

Phase 4

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain

City of Hope Medical Center10 enrolled1 locationNCT05376878

Recruiting

Phase 4

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more

Mayo Clinic75 enrolled1 locationNCT06764095

Completed

Phase 4

Bromocriptine effect on left ventricular hypertrophy in patients with diabetic nephropathy

Stage IV of chronic kidney diseaseType 2 diabetes mellitus (DM2)

Escuela Superior de Medicina del Instituto Politecnico Nacional (IPN)20 enrolled1 locationACTRN12610000779077

Completed

Phase 3Phase 4

A placebo-controlled trial to assess the effect of aspirin and fish oil (omega-3 fatty acids) in the prevention of early thrombosis in arterio-venous fistulae in patients with chronic kidney disease requiring haemodialysis

Early thrombosis in arterio-venous fistulae in patients with Stage IV or V chronic kidney disease requiring haemodialysis

Australasian Kidney Trials Network950 enrolled26 locationsACTRN12607000569404