Phase 2 Stem Cell Transplantation Clinical Trials
22 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 22 trials
Recruiting
Phase 1Phase 2
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 2
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Hematopoietic Stem Cell TransplantationImmunodeficiency
National Cancer Institute (NCI)54 enrolled1 locationNCT05027945
Recruiting
Phase 2
Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen
Peripheral Blood Stem Cell Transplantation
Chinese PLA General Hospital50 enrolled1 locationNCT05088226
Recruiting
Phase 2
Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients
Oral MucositisHematopoietic Stem Cell TransplantationStomatitis+1 more
The First Affiliated Hospital of Soochow University22 enrolled1 locationNCT07400328
Recruiting
Phase 2
G-CSF Combined With IL-11 on Hematopoietic Reconstitution After Autologous Hematopoietic Stem Cell Transplantation
Hematopoetic Stem Cell TransplantationHemato-oncologic PatientsMobilization of Hematopoietic Stem Cells (HSC) to Peripheral Blood (PB)
Fudan University224 enrolled3 locationsNCT07362810
Recruiting
Phase 2
Inotuzumab Ozogamicin in the Treatment of MRD+ After HSCT of ALL
ALLMRD-positiveHematopoietic Stem Cell Transplantation
Sheng-Li Xue, MD42 enrolled1 locationNCT05940961
Recruiting
Phase 2
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant
Acute Lymphoblastic LeukemiaAcute LeukemiaMyeloproliferative Neoplasm+14 more
Fred Hutchinson Cancer Center68 enrolled10 locationsNCT03779854
Recruiting
Phase 2
Phase 2 Trial of BN104 as Post-HSCT Maintenance in Acute Leukemia
Acute LeukemiaMenin InhibitorsPost Hematopoietic Stem Cell Transplantation+4 more
The First Affiliated Hospital of Soochow University60 enrolled1 locationNCT07101497
Recruiting
Phase 2
Vaccination Against Human Papillomavirus (HPV) After Allogeneic Stem Cell Transplantation
Myelodysplastic SyndromeAcute Myeloid LeukaemiaRecipients of Allogeneic Stem Cell Transplantation+1 more
Vastra Gotaland Region100 enrolled5 locationsNCT06793410
Recruiting
Phase 2
Demethylating Agents Combined With Venetoclax for High-risk T-cell Lymphoblastic Lymphoma/Leukemia Post-Transplant Relapse Prevention
RelapseT-cell Acute Lymphoblastic LeukemiaALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine59 enrolled1 locationNCT06686108
Recruiting
Phase 2
Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA
Hematopoietic Stem Cell TransplantationThrombotic Microangiopathies
Omeros Corporation18 enrolled16 locationsNCT05855083
Recruiting
Phase 2
Comparing the Therapeutic Effects of Using Ruxolitinib and Steroids Concurrently to Steroids Alone as Initial Treatment In Patients Diagnosed With Chronic Graft-versus-host Disease at a Grade of Moderate or Higher Severity
NeoplasmsGVHD - Graft-Versus-Host DiseaseHaematopoietic Stem Cell Transplantation
Byung-Sik Cho88 enrolled1 locationNCT06756061
Recruiting
Phase 2
Eltrombopag for Peripheral Blood Stem Cell Harvest
LymphomaPeripheral Blood Stem Cell Transplantation
National Taiwan University Hospital46 enrolled1 locationNCT05961410
Recruiting
Phase 2
Clinical Study of CAR-T Cell Therapy Following ASCT for R/R B-cell Non-Hodgkin's Lymphoma
Lymphoma, B-CellAutologous Stem Cell Transplantation
The First Affiliated Hospital of Soochow University64 enrolled1 locationNCT06381830
Recruiting
Phase 2
Feasibility of prebiotic fibre supplementation during allogeneic stem cell transplantation
allogeneic stem cell transplantation
Metro North Hospital and Health Service36 enrolled1 locationACTRN12624000262505
Recruiting
Phase 2
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression
Refractory Idiopathic Aplastic AnemiaHaploidentical Allogeneic Hematopoietic Stem Cell Transplantation
Assistance Publique - Hôpitaux de Paris31 enrolled35 locationsNCT05126849
Recruiting
Phase 2
An open label, study to evaluate the safety of Cannabidiol (CBD) for the prevention of Acute Graft-Versus-Host Disease (GVHD) after allogeneic hematopoietic cell transplantation.
Acute Graft Versus Host DiseaseHematopoietic Stem Cell Transplantation
Kalytera Therapeutics Israel Ltd36 enrolled2 locationsACTRN12619000623190
Completed
Phase 2Phase 3
Stem cell transplant influenza vaccination strategies
autologous haematopoietic stem cell transplantation (autoHSCT)
Peter MacCullum Cancer Institute70 enrolled1 locationACTRN12619000617167
Completed
Phase 2
A multi-centre phase II trial of early treatment intensification with R-ICE (rituximab – ifosfamide, carboplatin, etoposide) chemotherapy followed by BEAM ( BCNU(BCNU is Carmustine), etoposide, ara-C (ara-C is Cytarabine), melphalan) high dose chemotherapy and autologous stem cell transplantation for patients with poor prognosis diffuse large B-cell lymphoma
Patients with CD20+ diffuse large B cell lymphoma (DLBCL) with low intermediate, high intermediate, or high risk disease or low risk disease with bulky tumour (> 7.5 cm) who are considered fit and eligible for high dose chemotherapy (HDCT) with Z-BEAM ( Zevalin - BEAM ( BCNU(BCNU is Carmustine), etoposide, ara-C (ara-C is Cytarabine), melphalan) and autologous stem cell transplantation (ASCT).
Australasian Leukaemia and Lymphoma Group (ALLG)162 enrolled1 locationACTRN12609001077257
Recruiting
Phase 2
A Phase II Study of the Impact of Two Different Schedules of Thymoglobulin on the Incidence of Extensive Chronic Graft Verus Host Disease (GVHD) in Patients Undergoing Unrelated Donor or Mismatched Related Donor Stem Cell Transplantation
Chronic Graft versus Host Disease in Haematology Malignancy Patients receiving donor stem cell transplantation
The Royal Melbourne Hospital120 enrolled1 locationACTRN12609000173291