Phase 3 THA Clinical Trials

37 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 37 trials

Recruiting
Phase 3

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Beta-ThalassemiaMyelodysplastic Syndromes (MDS)Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Celgene665 enrolled143 locationsNCT04064060
Recruiting
Phase 3

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

methamphetamine abuseMethamphetamine Dependence
National Institute on Drug Abuse (NIDA)360 enrolled11 locationsNCT06233799
Recruiting
Phase 3

Parasitic Ulcer Treatment Trial

Acanthamoeba keratitis
Jeremy Keenan, MD, MPH232 enrolled17 locationsNCT06213649
Recruiting
Phase 3

Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea

FHA (Functional Hypothalamic Amenorrhea)
Massachusetts General Hospital114 enrolled2 locationsNCT06533865
Recruiting
Phase 3

MHB018A Treatment in Patients With Active Thyroid Eye Disease

Thyroid Associated Ophthalmopathies
Minghui Pharmaceutical (Hangzhou) Ltd108 enrolled1 locationNCT06989918
Recruiting
Phase 3

Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

Myasthaenia Gravis
Cartesian Therapeutics100 enrolled34 locationsNCT06799247
Recruiting
Phase 3

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Sickle Cell DiseaseThalassemia
Novo Nordisk A/S480 enrolled103 locationsNCT06609226
Recruiting
Phase 3

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Beta-ThalassemiaSickle Cell DiseaseHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated26 enrolled6 locationsNCT05477563
Recruiting
Phase 3

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546
Recruiting
Phase 2Phase 3

Divided or Single Exposure (DOSE) Study

Chronic PainOpioid-use DisorderMethadone
University of Maryland, Baltimore150 enrolled1 locationNCT05459402
Recruiting
Phase 3

Suzetrigine in Total Hip Arthroplasty

Total Hip Replacement SurgeryPainPain Management+13 more
Hospital for Special Surgery, New York210 enrolled1 locationNCT07226700
Recruiting
Phase 2Phase 3

Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo

Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 3

Efgartigimod in IVIG Dependent Myasthenia Gravis Patients

Myasthaenia Gravis
Clinique Neuro-Outaouais30 enrolled1 locationNCT06765161
Recruiting
Phase 2Phase 3

Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Thyroid DiseasesEndocrine System DiseasesThyroid Eye Disease+9 more
Sling Therapeutics, Inc.75 enrolled2 locationsNCT06112340
Recruiting
Phase 3

The Effect of Eplerenone on the Evolution of Vasculopathy in Renal Transplant Patients.

Kidney Transplantation for More Than One YearPatients with a Kidney Transplantation on Cyclosporine
Central Hospital, Nancy, France36 enrolled1 locationNCT04450953
Recruiting
Phase 3

Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial)

Thyroid Associated Ophthalmopathy
Janjira Petsuksiri68 enrolled1 locationNCT06392906
Recruiting
Phase 3

Clemastine Fumarate as Remyelinating Treatment in Internuclear Ophthalmoparesis and Multiple Sclerosis

Multiple SclerosisInternuclear Ophthalmoplegia
Amsterdam UMC, location VUmc80 enrolled1 locationNCT05338450
Recruiting
Phase 3

Treatment of Graves´ophthalmopathy with Simvastatin (GO-S)

Thyroid Associated OphthalmopathyGraves OphthalmopathyThyroid Associated Orbitopathy
Lund University80 enrolled1 locationNCT03131726
Completed
Phase 2Phase 3

Evaluating two doses of intravenous lidocaine infusion for relief of nerve-related pain that persists after trauma or surgery.

Peripheral neuropathic pain that persists after trauma or surgery.
Royal Brisbane and Women's Hospital40 enrolled1 locationACTRN12622000538741
Recruiting
Phase 3

Can a pre-conception weight loss program improve maternal and infant outcomes for women with overweight or obesity? A pragmatic randomised controlled trial (RCT).

Women with obesity BMI greater than 30kg/m2Women with overweight (BMI greater than 25kg/m2 to less than 30kg/m2 )
The University of Sydney1,927 enrolled6 locationsACTRN12620001238965