Early Phase 1 TME Clinical Trials

17 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 117 of 17 trials

Recruiting
Early Phase 1

Personalized DBS Targeting for Treating Depression

Treatment Resistant Depression (TRD)
Second Affiliated Hospital, School of Medicine, Zhejiang University5 enrolled1 locationNCT06784388
Recruiting
Early Phase 1

Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease

Post-Treatment Lyme Disease
State University of New York - Upstate Medical University44 enrolled1 locationNCT06611111
Recruiting
Early Phase 1

Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Calciphylaxis

EfficacyTreatmentChronic Kidney Diseases+3 more
The First Affiliated Hospital with Nanjing Medical University9 enrolled1 locationNCT04592640
Recruiting
Early Phase 1

Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer.

Colorectal, CancerDC-CIK TreatmentRegorafenib+2 more
JIANG LONGWEI14 enrolled1 locationNCT07343791
Recruiting
Early Phase 1

A Study of GC203 TIL in PDCA (RJ)

Pancreatic CancerTreatment Side EffectsTumor Infiltrating Lymphocytes+1 more
Shanghai Juncell Therapeutics10 enrolled1 locationNCT06828328
Recruiting
Early Phase 1

A Study of TIL in Advanced Solid Tumors (DFGD)

Advanced Solid TumorTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics30 enrolled1 locationNCT06488950
Recruiting
Early Phase 1

Propranolol for Misophonia

MisophoniaMisophonia TreatmentPropanolol
Bloom Mental Health, LLC20 enrolled1 locationNCT07271485
Recruiting
Early Phase 1

A Study of GC201 TIL in Advanced Gynecologic Tumors (10hospital)

Treatment Side EffectsEffects of ImmunotherapyAdvanced Gynecologic Tumors+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098171
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Melanoma (10hospital)

Advanced MelanomaTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098184
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Hepatobiliary-Pancreatic Cancers (10hospital)

Treatment Side EffectsEffects of ImmunotherapyTumor Infiltrating Lymphocyte+2 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098197
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Breast Cancer (10hospital)

Breast CancerAdvanced Breast CancerTreatment Side Effects+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05142475
Recruiting
Early Phase 1

The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain

To Evaluate the Effectiveness of Intra-canal Nano-ketrolac as a Medicament in Reducing Post-endodontic Pain in Patients Undergoing Root Canal Treatment
Al-Azhar University36 enrolled1 locationNCT07064083
Recruiting
Early Phase 1

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Advanced Solid TumorTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05087745
Recruiting
Early Phase 1

Using Chronobiology to Improve Lenvatinib Efficacy

Lenvatinib Treatment
Hadassah Medical Organization10 enrolled1 locationNCT06321120
Recruiting
Early Phase 1

The Role of Glutamatergic Function in the Pathophysiology of Treatment-resistant Schizophrenia

Treatment-resistant SchizophreniaHealthy (Controls)Treatment-responsive Schizophrenia
King's College London288 enrolled1 locationNCT06270108
Terminated
Early Phase 1

Exploratory trial to assess the efficacy and safety of Psilocybin-Assisted Psychotherapy (PAP) involving family-members compared to standard PAP, in adults with treatment-resistant major depressive disorder. (TRMDD).

Treatment-resistant major depressive disorder (TRMDD).
Reset Mind Science60 enrolled1 locationACTRN12623000618651
Completed
Early Phase 1

The buccal administration of a NanoCelle™ Cannabidiol formulation to healthy volunteers: a pharmacokinetic, safety and tolerability exploratory pilot study.

The Investigational Product may be indicated for insomniaThe Investigational Product may be indicated for the treatment of inflammatory painThe Investigational Product may be indicated for mood symptoms+1 more
Medlab Clinical16 enrolled1 locationACTRN12617001491358