Phase 1 Tooth Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1Phase 2
Study of Intrathecal ELP-02 for Charcot-Marie-Tooth Disease Type 4J (CMT4J)
Charcot-Marie-Tooth Disease Type 4J
Elpida Therapeutics SPC8 enrolled2 locationsNCT07447557
Recruiting
Phase 1Phase 2
Evaluate the Safety and Efficacy of EN001 in Patients With Charcot-Marie-Tooth Disease Type 1A(CMT1A) (Phase 1b: Open-label, Dose-escalation, Single-center; Phase 2a: Randomized, Double-blind, Placebo-controlled, Multicenter)
Charcot-Marie-Tooth Disease, Type 1A
ENCell27 enrolled3 locationsNCT06328712
Recruiting
Phase 1
A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A.
Charcot-Marie-Tooth Disease, Type 1A
Novartis Pharmaceuticals28 enrolled3 locationsNCT07140614
Recruiting
Phase 1Phase 2
Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing
Tooth ExtractionAlveolar Bone LossBone Regeneration
Al Salam University40 enrolled1 locationNCT07508033
Recruiting
Phase 1Phase 2
Safety and Performance, and Dose, of OsteoAdapt DE in Localized Alveolar Ridge Augmentations
Tooth Extraction Site HealingRidge AugmentationBone Graft
Theradaptive, Inc45 enrolled6 locationsNCT07078331
Recruiting
Phase 1Phase 2
Evaluation of Effect of Platelet-Rich Fibrin on Orthodontic Tooth Movement: a Split Mouth Randomised Controlled Trial
Rate of Tooth Movement in Orthodontic Patients
Dow University of Health Sciences15 enrolled1 locationNCT06634017
Withdrawn
Phase 1
Comparative assessment of the absorption of a generic formulation of a combination N-(4-hydroxyphenyl)acetamide/(RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid oral suspension against two innovator formulations administered simultaneously of N-(4-hydroxyphenyl)acetamide oral suspension and (RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid oral suspension conducted under fasting conditions in healthy volunteers.
(RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid is a nonsteroidal anti-inflammatory drug used for the temporary relief of fever, pain associated with teething, toothache, earache, sore throat, headache, minor ache, sprain, strain, cold and flu.N-(4-hydroxyphenyl)acetamide is an effective analgesic and antipyretic. It is indicated for the temporary relief of pain, discomfort associated with teething, headache, earache, immunisation, toothache, cold and flu, and it reduces fever.
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12621001446853