Urethral Stricture Clinical Trials

12 recruitingLast updated: May 13, 2026

There are 12 actively recruiting urethral stricture clinical trials across 8 countries. Studies span Not Applicable, Phase 4, Phase 1, Phase 3. Top locations include San Francisco, California, United States, Ghent, Belgium, Dallas, Texas, United States. Updated daily from ClinicalTrials.gov.


Urethral Stricture Trials at a Glance

12 actively recruiting trials for urethral stricture are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in San Francisco, Ghent, and Dallas. Lead sponsors running urethral stricture studies include Tanta University, University Hospital, Ghent, and Medical University of Graz.

Browse urethral stricture trials by phase

Treatments under study

About Urethral Stricture Clinical Trials

Looking for clinical trials for Urethral Stricture? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Urethral Stricture trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Urethral Stricture clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 4

Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters

Urethral Stricture
Urotronic Inc.34 enrolled9 locationsNCT05383274
Recruiting

Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction

Urethral Stricture
Ankara City Hospital Bilkent60 enrolled1 locationNCT07403786
Recruiting
Phase 4

Risk of Recurrent Urethral Stricture After Treatment With Paclitaxel-Coated Dilatation Balloon (Optilume) Compared With Non-coated Dilatation Balloon

Urethral Stricture
Vastra Gotaland Region230 enrolled4 locationsNCT06795074
Recruiting
Phase 3

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Urethral Stricture, Male
University of California, San Francisco60 enrolled2 locationsNCT05300685
Recruiting
Not Applicable

Bioengineered Collagen Implant for Urethral Stricture Repair

Urethral Stricture
Regenosca SA5 enrolled1 locationNCT05463991
Recruiting
Phase 1

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

Male Urogenital DiseasesUrologic DiseasesUrethral Stricture+1 more
Wake Forest University Health Sciences10 enrolled2 locationsNCT03258658
Recruiting
Not Applicable

Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture

UrethroplastyBuccal Mucosal GraftJoshi's Step+1 more
Tanta University50 enrolled1 locationNCT07088198
Recruiting
Not Applicable

Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture

UrethroplastyUrethral StricturePenile Skin+3 more
Tanta University80 enrolled1 locationNCT07074717
Recruiting
Not Applicable

Multi-stage Urethroplasty with Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second Stage

Urethral StrictureUrethra Stenosis
University Hospital, Ghent30 enrolled1 locationNCT04965025
Recruiting

Urethral Stricture Database

Urethral Stricture
Medical University of Graz500 enrolled1 locationNCT06362083
Recruiting

9000 URETHRA STUDY: a Study About Urethroplasty for Urethral Stricture Disease

Urethral Stricture
University Hospital, Ghent1,000 enrolled2 locationsNCT04071925
Recruiting

ERUPT Trial: Urethral scarring after radiation treatment for prostate cancer

Urethral StricturesProstate Cancer
Icon Cancer Foundation350 enrolled3 locationsACTRN12619000971134