5-Fluorouracil Clinical Trials
24 recruitingDrug
Phase 216Phase 36Phase 13Not Applicable2
Showing 1–20 of 24 trials
Recruiting
Phase 3
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Rectal AdenocarcinomaColon Adenocarcinoma
Merck Sharp & Dohme LLC477 enrolled217 locationsNCT06997497
Recruiting
Phase 2
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
Colorectal, Cancer
Ono Pharmaceutical Co., Ltd.144 enrolled39 locationsNCT06948448
Recruiting
Phase 2Phase 3
A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02)
Esophageal Squamous Cell Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd.90 enrolled1 locationNCT07554456
Recruiting
Phase 1
Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies
Colorectal, CancerOvarian CancerPeritoneal Carcinomatosis+4 more
National Cancer Institute (NCI)60 enrolled1 locationNCT04847063
Recruiting
Phase 3
Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )
Pancreatic CancerPancreatic Ductal Adenocarcinoma (PDAC)Pancreatic Adenocarcinoma Metastatic+5 more
Revolution Medicines, Inc.670 enrolled4 locationsNCT07621718
Recruiting
Phase 2
A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer
Esophageal CancerGastric AdenocarcinomaHER2 Gene Mutation
Memorial Sloan Kettering Cancer Center49 enrolled10 locationsNCT06123338
Recruiting
Phase 3
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
Esophageal CancerGastric CancerGastroesophageal Junction Adenocarcinoma
AstraZeneca2,130 enrolled286 locationsNCT07431281
Recruiting
Phase 2
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Colorectal, CancerGastric CancerBiliary Tract Cancer+4 more
AstraZeneca454 enrolled96 locationsNCT05489211
Recruiting
Phase 2
Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Gastric Cancer
AstraZeneca163 enrolled44 locationsNCT05702229
Recruiting
Phase 2
Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma
Locally Advanced Pancreatic AdenocarcinomaMetastatic Pancreatic Adenocarcinoma
Medical University of South Carolina52 enrolled2 locationsNCT07076212
Recruiting
Phase 2
5-Fluorouracil Response and Optimization STudy (The FROST Trial)
Squamous Cell Carcinoma of Head and NeckMetastatic Squamous Cell CarcinomaRecurrent Squamous Cell Carcinoma of the Head and Neck
Washington University School of Medicine46 enrolled1 locationNCT07419464
Recruiting
Phase 2
Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA
Esophagus CancerStomach CancerStomach Cancer Stage IV
Massachusetts General Hospital40 enrolled2 locationsNCT07070466
Recruiting
Phase 1Phase 2
A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors
Advanced Solid Tumors
Astellas Pharma Global Development, Inc.366 enrolled44 locationsNCT05083481
Recruiting
Phase 2
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Gastric CancerGastroesophageal-junction CancerBiliary Tract Cancer+1 more
AstraZeneca224 enrolled52 locationsNCT06219941
Recruiting
Not Applicable
Adaptive Radiation in Anal Cancer
Anal Squamous Cell Carcinoma
Columbia University20 enrolled1 locationNCT05838391
Recruiting
Phase 1
Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies
Gastroesophageal Junction AdenocarcinomaPancreatic AdenocarcinomaAdenocarcinoma
University of Chicago54 enrolled1 locationNCT04361708
Recruiting
Phase 2
Safety and Efficacy of IB-FOLFIRI in BRAF V600E-Mutant Metastatic Colorectal Cancer
BRAF V600 Colorectal Cancer
Sun Yat-sen University20 enrolled1 locationNCT07150247
Recruiting
Phase 2
Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal Adenocarcinoma
University of Miami50 enrolled1 locationNCT07096362
Recruiting
Phase 3
HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT)
Gastric CancerGastroesophageal Junction Adenocarcinoma
Krankenhaus Nordwest200 enrolled15 locationsNCT04447352
Recruiting
Phase 2
Nivolumab in Children and Adults With Nasopharyngeal Carcinoma
Nasopharyngeal CancerNasopharyngeal CarcinomaNasopharynx Cancer+1 more
German Society for Pediatric Oncology and Hematology GPOH gGmbH57 enrolled31 locationsNCT06019130