Binimetinib Clinical Trials
11 recruitingDrug
Phase 27Phase 13Phase 31
Showing 1–11 of 11 trials
Recruiting
Phase 2
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Malignant Female Reproductive System Neoplasm+12 more
National Cancer Institute (NCI)2,900 enrolled479 locationsNCT05564377
Recruiting
Phase 2
Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic MelanomaPathologic Stage IV Cutaneous Melanoma AJCC v8
M.D. Anderson Cancer Center35 enrolled1 locationNCT05026983
Recruiting
Phase 1
Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma
Metastatic MelanomaBRAF Gene Mutation
Rina Plattner30 enrolled4 locationsNCT04903119
Recruiting
Phase 1Phase 2
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Cutaneous MelanomaMetastatic Uveal Melanoma
IDEAYA Biosciences336 enrolled15 locationsNCT03947385
Recruiting
Phase 1
Study of Binimetinib in Combination With Pembrolizumab in Advanced Non-Small Cell Lung Cancer
Non-small Cell Carcinoma
University Health Network, Toronto40 enrolled4 locationsNCT03991819
Recruiting
Phase 2
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic MelanomaPathologic Stage IV Cutaneous Melanoma AJCC v8+4 more
SWOG Cancer Research Network112 enrolled331 locationsNCT04511013
Recruiting
Phase 2
Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma
Melanoma Stage IVMelanoma Stage III
University of California, San Francisco25 enrolled2 locationsNCT04598009
Recruiting
Phase 2
Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer
Stage III Breast CancerTriple-Negative Breast CarcinomaRecurrent Breast Carcinoma+6 more
Laura Huppert, MD, BA150 enrolled12 locationsNCT03971409
Recruiting
Phase 3
Personalized Medicine for Advanced Biliary Cancer Patients
Biliary Tract Neoplasms
UNICANCER800 enrolled69 locationsNCT05615818
Recruiting
Phase 2
Melanoma Metastasized to the Brain and Steroids
Malignant Melanoma
Inge Marie Svane80 enrolled3 locationsNCT03563729
Recruiting
Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment
Melanoma Stage IVMelanoma Stage III
Pierre Fabre Pharma GmbH750 enrolled59 locationsNCT04045691