Dupilumab Clinical Trials

38 recruitingDrug
Phase 210Phase 48Phase 36Early Phase 12Phase 11

Showing 120 of 38 trials

Recruiting
Phase 3

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis
AbbVie675 enrolled148 locationsNCT06461897
Recruiting
Phase 4

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled53 locationsNCT07053423
Recruiting
Phase 3

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

Pruritus
Sanofi284 enrolled90 locationsNCT05263206
Recruiting
Phase 4

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

Asthma
Sanofi1,324 enrolled249 locationsNCT05097287
Recruiting
Phase 3

Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)

AsthmaWheezing
Sanofi90 enrolled74 locationsNCT06191315
Recruiting
Phase 2

A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis
Innovent Biologics (Suzhou) Co. Ltd.403 enrolled1 locationNCT07330934
Recruiting
Phase 3

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Chronic Spontaneous Urticaria (CSU)
Novartis Pharmaceuticals400 enrolled114 locationsNCT06868212
Recruiting

The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis
Sanofi184 enrolled1 locationNCT07467564
Recruiting

A Non-interventional Observational Study to Assess Long-term Efficacy and Safety of Dupilumab for the Treatment of Patients (>= 12 Years) With Eosinophilic Esophagitis Under Real-world-conditions in Germany

Sanofi150 enrolled1 locationNCT06695897
Recruiting
Phase 2

Dupilumab Effects Against Aeroallergen Challenge

Asthma, Allergic
The University of Texas Health Science Center at San Antonio88 enrolled2 locationsNCT05720325
Recruiting
Phase 2

Dupilumab in the Treatment of Pediatric Alopecia Areata

Alopecia Areata
Icahn School of Medicine at Mount Sinai76 enrolled5 locationsNCT05866562
Recruiting

A Study to Describe the Real-world Effectiveness, Safety and Patterns of Use of Dupilumab in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria
Sanofi400 enrolled1 locationNCT07316114
Recruiting
Phase 2

A Proof-of-Concept Study of IBI3002 in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis
Innovent Biologics (Suzhou) Co. Ltd.120 enrolled1 locationNCT07399067
Recruiting

Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis

Chronic Rhinosinusitis With Nasal Polyps
Montefiore Medical Center60 enrolled1 locationNCT05246267
Recruiting
Phase 3

A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis

Prurigo Nodularis
Sanofi18 enrolled14 locationsNCT06293053
Recruiting

Study to Evaluate Long-term Effectiveness and Safety, Patient Characteristics and Subjective Patient-reported Outcomes of Dupilumab in Patients With Chronic Obstructive Pulmonary Disease (COPD) Under Real-world Conditions

Chronic Obstructive Pulmonary Disease (COPD)
Sanofi350 enrolled18 locationsNCT07052396
Recruiting

Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo Nodularis

Prurigo Nodularis (PN)
UMC Utrecht40 enrolled1 locationNCT07276425
Recruiting
Phase 2

Dupilumab Therapy in Nephrotic Syndrome in Children

Nephrotic Syndrome in ChildrenNephrotic Syndrome Steroid-Dependent
National University Hospital, Singapore66 enrolled2 locationsNCT07091175
Recruiting
Phase 2Phase 3

Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

Skin InflammationAllergic Contact Dermatitis
Wei-Che Ko45 enrolled1 locationNCT05535738
Recruiting
Phase 4

Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

Asthma
Sally E. Wenzel MD30 enrolled1 locationNCT04743791