Mesna Clinical Trials
22 recruitingDrug
Phase 113Phase 211Phase 31Early Phase 11
Showing 1–20 of 22 trials
Recruiting
Phase 1
CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma
Hematologic MalignancyRelapsed Pediatric ALLHematopoietic Cell Transplantation
St. Jude Children's Research Hospital60 enrolled1 locationNCT07257419
Recruiting
Phase 1Phase 2
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
Hematologic Neoplasms
National Cancer Institute (NCI)320 enrolled2 locationsNCT04959175
Recruiting
Phase 2
CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia
Acute Lymphoblastic LeukemiaRefractory Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital25 enrolled1 locationNCT06847269
Recruiting
Phase 1
CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)
B-ALLAML/MDST-ALL+1 more
St. Jude Children's Research Hospital108 enrolled2 locationsNCT04318678
Recruiting
Phase 1
CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)
Acute Myeloid LeukemiaAMLRefractory Acute Myeloid Leukemia
CERo Therapeutics Holdings, Inc.18 enrolled4 locationsNCT06834282
Recruiting
Phase 1Phase 2
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 3
Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI)348 enrolled211 locationsNCT04530565
Recruiting
Phase 2
High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly
MyelofibrosisSplenomegaly
M.D. Anderson Cancer Center30 enrolled1 locationNCT06345495
Recruiting
Early Phase 1
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
CNS Embryonal TumorCNS, Medulloblastoma
C17 Council15 enrolled12 locationsNCT06942039
Recruiting
Phase 2
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
Central Nervous System Nongerminomatous Germ Cell TumorChoriocarcinomaEmbryonal Carcinoma+7 more
Children's Oncology Group160 enrolled165 locationsNCT04684368
Recruiting
Phase 1Phase 2
Stem Cell Transplantation in Crohn's Disease
Crohn Disease
Cedars-Sinai Medical Center15 enrolled1 locationNCT04224558
Recruiting
Phase 1
CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies
LymphomaMDSHematologic Malignancy+2 more
St. Jude Children's Research Hospital18 enrolled1 locationNCT06326463
Recruiting
Phase 2
Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma
Lymphoma
M.D. Anderson Cancer Center40 enrolled1 locationNCT02106988
Recruiting
Phase 1
TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies
Hematologic Malignancy
St. Jude Children's Research Hospital30 enrolled1 locationNCT07052370
Recruiting
Phase 1
Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia
Acute Lymphoblastic Leukemia, in Relapse
St. Jude Children's Research Hospital60 enrolled1 locationNCT04881240
Recruiting
Phase 1Phase 2
Autologous Stem Cell Transplantation for Crohn's Disease
Crohn's Disease
Paul Szabolcs20 enrolled2 locationsNCT00692939
Recruiting
Phase 1
CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia
Acute Lymphoblastic LeukemiaRecurrent Acute Lymphoblastic LeukemiaRecurrent B Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital30 enrolled1 locationNCT06777979
Recruiting
Phase 1
IS-free Treg HaploHCT
Stem Cell Transplant Complications
Dana-Farber Cancer Institute30 enrolled1 locationNCT04678401
Recruiting
Phase 2
Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
Interstitial Lung DiseasePulmonary HypertensionSystemic Sclerosis+1 more
Paul Szabolcs8 enrolled3 locationsNCT03630211
Recruiting
Umbilical Cord Blood Transplantation From Unrelated Donors
Solid TumorMultiple MyelomaAcute Leukemia+7 more
University of Rochester30 enrolled1 locationNCT03016806