Patritumab deruxtecan Clinical Trials

6 recruitingBiologic
Phase 25Phase 14Phase 31

Showing 16 of 6 trials

Recruiting
Phase 1Phase 2

A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)

Lung Neoplasm Malignant
Merck Sharp & Dohme LLC190 enrolled4 locationsNCT07286149
Recruiting
Phase 3

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Breast Neoplasms
Merck Sharp & Dohme LLC1,000 enrolled159 locationsNCT07060807
Recruiting
Phase 1Phase 2

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

Gastrointestinal Cancer
Merck Sharp & Dohme LLC180 enrolled62 locationsNCT06596694
Recruiting
Phase 2

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

Breast CancerBreast Neoplasms
Merck Sharp & Dohme LLC372 enrolled17 locationsNCT06797635
Recruiting
Phase 1Phase 2

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

Breast CancerBreast Neoplasms
Merck Sharp & Dohme LLC81 enrolled17 locationsNCT06686394
Recruiting
Phase 1Phase 2

Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd

Breast Cancer MetastaticAdvanced Breast CancerHER2-positive Metastatic Breast Cancer+1 more
Gustave Roussy, Cancer Campus, Grand Paris152 enrolled1 locationNCT06298084