Paid Clinical Trials for Healthy Volunteers

1,168 recruiting

Phase 1, dietary, observational, and biomarker studies that pay healthy adults.


Compensation

Most studies compensate participants for time and travel. Specific amounts are set by each sponsor and disclosed in the consent form.

Reviewed studies

All listings are registered on public trial registries and approved by an IRB or HREC before enrolling participants.

Time commitments vary

From a single outpatient visit to multi-week inpatient stays. Read the time commitment in each listing before applying.

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Recently updated studies

Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting

Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies

Healthy VolunteersHIV
National Institute of Allergy and Infectious Diseases (NIAID)3,000 enrolled1 locationNCT00114647
Recruiting

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

NeoplasmsHealthy VolunteersHematologic Neoplasms
National Heart, Lung, and Blood Institute (NHLBI)6,000 enrolled1 locationNCT00071045
Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting

International (Pediatric) Peritoneal Biobank

HealthyKidney Failure, ChronicTransplantation+1 more
Heidelberg University500 enrolled26 locationsNCT01893710
Recruiting

Validation of Energy Expenditure Measures Study

HealthyObesity Prevention
University of Leipzig34 enrolled1 locationNCT07155564
Recruiting
Phase 1

A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults

HealthyOverweight and Obese Adults
Syntis Bio64 enrolled1 locationNCT07307274
Recruiting

Characterization of Diseases With Salivary Gland Involvement

Healthy VolunteerSjogren's SyndromeSalivary Gland Disease
National Institute of Dental and Craniofacial Research (NIDCR)1,150 enrolled1 locationNCT02327884
Recruiting
Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting

Children s Growth and Behavior Study

ObesityHealthy VolunteersEating Behaviors
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)1,500 enrolled1 locationNCT02390765
Recruiting
Not Applicable

Clinical Explorative Optical Breast Investigations

Benign Breast TumorsMalignant Breast TumoursHealthy
Region Skane90 enrolled1 locationNCT06857669
Recruiting
Not Applicable

Non-invasive BCI-controlled Assistive Devices

Traumatic Brain InjuryHealthyMovement Disorders+6 more
University of Texas at Austin100 enrolled1 locationNCT05183152

Common questions

What is a healthy-volunteer clinical trial?

A study that enrolls people without the condition being tested — typically Phase 1 drug-safety trials, dietary studies, observational research, or biomarker studies. Participants are usually compensated for time and travel.

How are participants paid?

Compensation varies by study. Phase 1 inpatient studies often pay $1,000–$5,000+ for full participation; outpatient and dietary studies may pay $50–$500 per visit. Specific compensation is set by each study sponsor and documented in the consent form.

Is it safe?

All listed studies are registered on public clinical trial registries (ClinicalTrials.gov etc.) and have been approved by an Institutional Review Board (IRB) or Human Research Ethics Committee (HREC). Read the full informed-consent document before enrolling.

How do I apply?

Each study listing links to the official trial record, where the recruiting site's contact details are published. Contact the site directly to start their screening process.

What is Phase 1?

The first stage of human testing for a new drug or device, focused on safety and dosing. Phase 1 trials usually enroll a small number of healthy volunteers under close medical supervision.