Paid Clinical Trials for Healthy Volunteers
Phase 1, dietary, observational, and biomarker studies that pay healthy adults.
Compensation
Most studies compensate participants for time and travel. Specific amounts are set by each sponsor and disclosed in the consent form.
Reviewed studies
All listings are registered on public trial registries and approved by an IRB or HREC before enrolling participants.
Time commitments vary
From a single outpatient visit to multi-week inpatient stays. Read the time commitment in each listing before applying.
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Recently updated studies
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Neurobiology of Suicide
Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study
A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity
A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial
Predicting Future Errors During Skill Performance
Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers
Guides for healthy volunteers
Common questions
What is a healthy-volunteer clinical trial?
A study that enrolls people without the condition being tested — typically Phase 1 drug-safety trials, dietary studies, observational research, or biomarker studies. Participants are usually compensated for time and travel.
How are participants paid?
Compensation varies by study. Phase 1 inpatient studies often pay $1,000–$5,000+ for full participation; outpatient and dietary studies may pay $50–$500 per visit. Specific compensation is set by each study sponsor and documented in the consent form.
Is it safe?
All listed studies are registered on public clinical trial registries (ClinicalTrials.gov etc.) and have been approved by an Institutional Review Board (IRB) or Human Research Ethics Committee (HREC). Read the full informed-consent document before enrolling.
How do I apply?
Each study listing links to the official trial record, where the recruiting site's contact details are published. Contact the site directly to start their screening process.
What is Phase 1?
The first stage of human testing for a new drug or device, focused on safety and dosing. Phase 1 trials usually enroll a small number of healthy volunteers under close medical supervision.