CHU de Nantes

Nantes, France

30 recruiting

Showing 120 of 30 trials

Recruiting
Phase 2

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
Nurix Therapeutics, Inc.100 enrolled18 locationsNCT07221500
Recruiting
Phase 1

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 3

COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes

Cardiovascular DiseasesDiabete Type 2
Montreal Heart Institute10,000 enrolled39 locationsNCT05633810
Recruiting
Phase 1Phase 2

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Non-small Cell Lung Cancer (NSCLC)KRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more
Revolution Medicines, Inc.616 enrolled89 locationsNCT06162221
Recruiting
Not Applicable

Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease

Parkinson DiseaseREM Sleep Behavior Disorder (iRBD)
Assistance Publique - Hôpitaux de Paris457 enrolled6 locationsNCT06582121
Recruiting
Phase 2

Reduction in the Number of Chemotherapy Cycles in Combination With Pembrolizumab in First-line Treatment of PD-L1-positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinomas

Squamous Cell Carcinoma of Head and Neck
Institut Claudius Regaud86 enrolled14 locationsNCT06557889
Recruiting
Not Applicable

Rheopheresis as Adjuvant Treatment of Calciphylaxis

Rare DiseasesEnd Stage Renal DiseaseMetabolic Disorder
University Hospital, Lille138 enrolled29 locationsNCT04654000
Recruiting
Phase 2

Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT

Acute Myeloid Leukemia in Remission
Nantes University Hospital302 enrolled23 locationsNCT05917405
Recruiting
Phase 3

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

Metastatic Non Small Cell Lung Cancer
Daiichi Sankyo740 enrolled243 locationsNCT05215340
Recruiting
Not Applicable

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial

Mitral Regurgitation
Medtronic Cardiovascular400 enrolled37 locationsNCT05496998
Recruiting
Not Applicable

Study Assessing PET Imaging With Zirconium-labelled Girentuximab in Patients With HCC, ICC or NEN

Neuroendocrine TumorsHepatocellular Carcinoma (HCC)Intrahepatic Cholangiocarcinoma (Icc)
Nantes University Hospital60 enrolled2 locationsNCT06735560
Recruiting

Ovarian Reserve and Semen Parameters Evolution During Adjuvant Therapy in Melanoma

Melanoma
Assistance Publique Hopitaux De Marseille80 enrolled12 locationsNCT05429138
Recruiting
Phase 1Phase 2

A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Pancreatic Ductal Adenocarcinoma (PDAC)Triple Negative Breast Cancer(TNBC)Colorectal Cancer (CRC)+6 more
ITM Oncologics GmbH270 enrolled10 locationsNCT05706129
Recruiting
Not Applicable

[68Ga]Ga-PSMA PET/CT in Hepatocellular Carcinoma: Impact of Multiparametric Dynamic Whole-body Imaging and Kinetic Modeling.

HCC - Hepatocellular Carcinoma
Nantes University Hospital40 enrolled2 locationsNCT06999837
Recruiting
Phase 3

Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis

Rheumatoid Arthritis
University Hospital, Montpellier220 enrolled17 locationsNCT05428488
Recruiting
Phase 2

Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial

Hepatocellular Carcinoma
University Hospital, Montpellier202 enrolled19 locationsNCT04727307
Recruiting

UroCCR Database: French Research Network for Kidney Cancer -UroCCR

Kidney Cancer
University Hospital, Bordeaux30,000 enrolled58 locationsNCT03293563
Recruiting

French Colorectal ESD Cohort in Experts Centers

Cancer ColorectalPolyps ColorectalEndoscopic Submucosal Resection
University Hospital, Limoges1,200 enrolled25 locationsNCT04592003
Recruiting
Not Applicable

Optimization of the Surgical Care Pathway for Kidney Tumors by Digitizing Perioperative Nursing Coordination (UroCCR 126)

Digitizing Perioperative Nursing Coordination
University Hospital, Bordeaux1,307 enrolled11 locationsNCT06047600
Recruiting
Phase 1Phase 2

Study Assessing RLT Using [177Lu]Lu-PentixaTher for Relapsed/Refractory CXCR4+ Acute Leukemia.

Acute Leukemia
Nantes University Hospital21 enrolled4 locationsNCT06356922