Medisch Spectrum Twente

Enschede, Netherlands

23 recruiting

Showing 120 of 44 trials

Recruiting
Phase 3

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Metastatic Colorectal Cancer
Amgen450 enrolled286 locationsNCT06252649
Recruiting
Phase 3

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled596 locationsNCT07037459
Recruiting
Phase 3

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Carcinoma, Non-Small Cell LungNeoplasm Metastasis
Eli Lilly and Company1,264 enrolled422 locationsNCT06119581
Recruiting
Phase 3

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Acute Myeloid Leukemia
University of Ulm650 enrolled91 locationsNCT04628026
Recruiting
Phase 3

NO Re-excision MelanomA - NORMA 2

Melanoma (Skin Cancer)
Marieke Goodijk1,749 enrolled21 locationsNCT07530887
Recruiting
Not Applicable

Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation

Myocardial InfarctionSudden Cardiac Death
Charite University, Berlin, Germany3,595 enrolled86 locationsNCT05665608
Recruiting
Not Applicable

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Ovarian CancerBRCA1 Gene MutationBRCA2 Gene Mutation+3 more
University Medical Center Nijmegen3,000 enrolled66 locationsNCT04294927
Recruiting
Phase 3

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

Polycythemia Vera
Italfarmaco220 enrolled90 locationsNCT06093672
Recruiting
Not Applicable

Anastomotic Leakage Prevention by Endovascular Stenting of the Superior Mesenteric Artery

Colorectal SurgeryMesenteric Vascular DiseasePreventive Intervention
Medisch Spectrum Twente360 enrolled10 locationsNCT07486570
Recruiting
Not Applicable

Coeliac Artery Release or Sham Operation

Median Arcuate Ligament SyndromeMesenteric IschemiaDunbar Syndrome+2 more
Medisch Spectrum Twente70 enrolled1 locationNCT05468580
Recruiting
Not Applicable

The Effect of Continuous Versus Intermittent Enteral Nutrition on Metabolic Outcomes in Critically Ill Patients

Critical Illness
Gelderse Vallei Hospital124 enrolled5 locationsNCT07173504
Recruiting

Terumo Aortic Global Endovascular Registry

SurgeryAbdominal Aortic AneurysmThoracic Aortic Aneurysm
Vascutek Ltd.1,000 enrolled58 locationsNCT04246463
Recruiting
Phase 3

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

First Progression of Glioblastoma
European Organisation for Research and Treatment of Cancer - EORTC411 enrolled43 locationsNCT05904119
Recruiting
Phase 2

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

InfectionsAcute Respiratory Distress Syndrome
BioAegis Therapeutics Inc.600 enrolled76 locationsNCT05947955
Recruiting
Not Applicable

Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm

Bladder CancerMuscle Invasive Bladder Cancer
Radboud University Medical Center360 enrolled19 locationsNCT05779631
Recruiting
Phase 3

Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer

Prostate Cancer
Nick Beije400 enrolled26 locationsNCT07260435
Recruiting
Phase 4

REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Axial Spondyloarthritis (AxSpA)
Sint Maartenskliniek200 enrolled7 locationsNCT07160231
Recruiting
Phase 3

Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive

Female Contraception
Leiden University Medical Center1,186 enrolled14 locationsNCT06394999
Recruiting

Translesional PRESSURE Measurements to Assess Clinical Relevance of a Mesenteric Artery Stenosis (PRESSURE-study)

Chronic Mesenteric IschemiaIschemia, Mesenteric
Erasmus Medical Center125 enrolled3 locationsNCT07059520
Recruiting

Promoting Early Diagnosis of Chronic Mesenteric Ischemia

Chronic Mesenteric Ischemia
Erasmus Medical Center296 enrolled4 locationsNCT05735002