National Institutes of Health Clinical Center

Bethesda, Maryland, United States

247 recruiting

Showing 120 of 637 trials

Recruiting
Phase 1

PET Imaging of Noradrenergic Transmission in the Brain

Healthy
National Institute of Mental Health (NIMH)40 enrolled1 locationNCT07686393
Recruiting

Phenotype/Genotype Correlations in Movement Disorders

Movement Disorder
National Institute of Neurological Disorders and Stroke (NINDS)2,500 enrolled1 locationNCT00018889
Recruiting
Not Applicable

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

eosinophilic esophagitisDysphagia
National Institute of Allergy and Infectious Diseases (NIAID)70 enrolled3 locationsNCT07027826
Recruiting
Phase 1Phase 2

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Myelodysplastic Syndromes
National Cancer Institute (NCI)160 enrolled1 locationNCT06303193
Recruiting

Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques

TicsFunctional Tics
National Institute of Neurological Disorders and Stroke (NINDS)75 enrolled1 locationNCT07137442
Recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Staphylococcal Infections
National Institute of Allergy and Infectious Diseases (NIAID)500 enrolled2 locationsNCT06479837
Recruiting
Phase 1Phase 2

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Hematologic Neoplasms
National Cancer Institute (NCI)430 enrolled1 locationNCT05327023
Recruiting

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Gulf War Illness
National Institute of Neurological Disorders and Stroke (NINDS)85 enrolled1 locationNCT05375812
Recruiting
Early Phase 1

Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort

Fatigue Syndrome, Chronic
National Institute of Neurological Disorders and Stroke (NINDS)47 enrolled1 locationNCT06472622
Recruiting
Not Applicable

Deep Brain Stimulation Therapy in Movement Disorders

Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)300 enrolled1 locationNCT02119611
Recruiting
Phase 1

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

DementiaALSMild Cognitive Impairment+2 more
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations

Lyme Disease
National Institute of Allergy and Infectious Diseases (NIAID)800 enrolled1 locationNCT00001539
Recruiting
Not Applicable

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

ObesityOverweight
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)100 enrolled1 locationNCT06044935
Recruiting
Phase 2

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting
Phase 1

Evaluation of [11C]ZTP-1 to Image PDE4B

Healthy
National Institute of Mental Health (NIMH)40 enrolled1 locationNCT07625345
Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Alcohol Use Disorder
National Institute of Mental Health (NIMH)30 enrolled1 locationNCT06795581
Recruiting
Phase 2

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)354 enrolled2 locationsNCT02579967
Recruiting
Phase 2

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Solid NeoplasmMalignant Female Reproductive System NeoplasmRecurrent Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI)70 enrolled188 locationsNCT06126276
Recruiting

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Trisomy 8 MosaicismTrisomy 8 Associated Autoinflammatory DiseaseMucosal Ulcerations
National Institute of Allergy and Infectious Diseases (NIAID)750 enrolled1 locationNCT07683104
Recruiting

Survey to Determine Incarcerated Persons' Views on Surrogate Decision Making

Healthy Volunteers
National Institutes of Health Clinical Center (CC)75,000 enrolledNCT07751731