Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom

29 recruiting

Showing 120 of 36 trials

Recruiting
Phase 2

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

Primary Biliary CholangitisPBC
Mirum Pharmaceuticals, Inc.260 enrolled130 locationsNCT05050136
Recruiting

Drug-induced Liver Injury: Itching Study

University of Nottingham50 enrolled1 locationNCT06446609
Recruiting
Phase 3

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Endometrial Cancer
BioNTech SE480 enrolled132 locationsNCT06340568
Recruiting
Phase 3

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

Adult Acute Myeloid Leukemia
Priothera SAS366 enrolled108 locationsNCT05429632
Recruiting
Phase 3

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany264 enrolled133 locationsNCT06463587
Recruiting
Phase 2Phase 3

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE350 enrolled193 locationsNCT04534205
Recruiting
Phase 3

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+4 more
Janssen Research & Development, LLC700 enrolled174 locationsNCT01804686
Recruiting

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma
Janssen Pharmaceutica N.V., Belgium300 enrolled87 locationsNCT05160584
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199
Recruiting
Phase 3

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

Lymphoma
SecuraBio124 enrolled44 locationsNCT06522737
Recruiting
Phase 2

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations
Taiho Oncology, Inc.220 enrolled80 locationsNCT05967689
Recruiting
Phase 1Phase 2

PS-002 for the Treatment of IgA Nephropathy in Adults

Immunoglobulin A (IgA) Nephropathy
Purespring Therapeutics Limited32 enrolled11 locationsNCT07182227
Recruiting
Not Applicable

Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers

Differentiated Thyroid Cancer
University College, London456 enrolled33 locationsNCT05604963
Recruiting
Phase 2

A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
MeiraGTx, LLC276 enrolled33 locationsNCT05926765
Recruiting

Faecal Immunochemical Tests (FIT) for Surveillance After Colorectal Cancer (CRC) Study

Colorectal Cancer (CRC)
Nottingham University Hospitals NHS Trust1,000 enrolled1 locationNCT06689293
Recruiting
Phase 3

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Atrial FibrillationStrokeBleeding
Icahn School of Medicine at Mount Sinai3,200 enrolled101 locationsNCT04045665
Recruiting
Phase 1Phase 2

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Acute Myeloid LeukemiaNon-Hodgkin LymphomaMultiple Myeloma+3 more
CellCentric Ltd.250 enrolled39 locationsNCT04068597
Recruiting
Phase 3

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole

Idiopathic Pulmonary Fibrosis
Norfolk and Norwich University Hospitals NHS Foundation Trust298 enrolled57 locationsNCT04965298
Recruiting

Effective Dosing of Burosumab in XLH

X-linked Hypophosphatemia (XLH)
University of Nottingham120 enrolled1 locationNCT07183579
Recruiting
Not Applicable

TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety

DepressionAnxietyAnhedonia+3 more
BlueSkeye AI125 enrolled2 locationsNCT06364488