Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom

29 recruiting

Showing 120 of 38 trials

Recruiting
Phase 3

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Acute Myeloid Leukemia, Adult
Stichting Hemato-Oncologie voor Volwassenen Nederland448 enrolled201 locationsNCT06652438
Recruiting
Phase 3

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+4 more
Janssen Research & Development, LLC700 enrolled175 locationsNCT01804686
Recruiting

Drug-induced Liver Injury: Itching Study

PruritusDrug-Induced Liver Injury
University of Nottingham50 enrolled1 locationNCT06446609
Recruiting
Phase 3

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany264 enrolled145 locationsNCT06463587
Recruiting
Phase 2Phase 3

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE350 enrolled195 locationsNCT04534205
Recruiting
Phase 3

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Endometrial Cancer
BioNTech SE480 enrolled171 locationsNCT06340568
Recruiting
Phase 3

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

Adult Acute Myeloid Leukemia
Priothera SAS366 enrolled111 locationsNCT05429632
Recruiting
Not Applicable

ConvaVAC™ Ag+ Negative Pressure Wound Therapy System in Chronic Wounds

Venous Leg Ulcer (VLU)
ConvaTec Inc.87 enrolled7 locationsNCT07342049
Recruiting

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma
Janssen Pharmaceutica N.V., Belgium300 enrolled90 locationsNCT05160584
Recruiting
Phase 1Phase 2

PS-002 for the Treatment of IgA Nephropathy in Adults

Immunoglobulin A (IgA) Nephropathy
Purespring Therapeutics Limited32 enrolled10 locationsNCT07182227
Recruiting
Phase 3

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Atrial FibrillationStrokeBleeding
Icahn School of Medicine at Mount Sinai3,200 enrolled106 locationsNCT04045665
Recruiting
Phase 2

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations
Taiho Oncology, Inc.220 enrolled80 locationsNCT05967689
Recruiting
Phase 1Phase 2

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Acute Myeloid LeukemiaNon-Hodgkin LymphomaMultiple Myeloma+3 more
CellCentric Ltd.250 enrolled39 locationsNCT04068597
Recruiting
Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis

Multiple Sclerosis
Hoffmann-La Roche75 enrolled12 locationsNCT07667322
Recruiting
Phase 3

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)

Cytomegalovirus (CMV)
Takeda80 enrolled53 locationsNCT05319353
Recruiting
Phase 2

A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

Primary Biliary CholangitisPBC
Mirum Pharmaceuticals, Inc.260 enrolled130 locationsNCT05050136
Recruiting

Effective Dosing of Burosumab in XLH

X-linked Hypophosphatemia (XLH)
University of Nottingham120 enrolled1 locationNCT07183579
Recruiting
Phase 2

Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

Refractory Follicular LymphomaRelapsed Follicular Lymphoma
University of Birmingham284 enrolled25 locationsNCT05848765
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199
Recruiting
Phase 3

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

Lymphoma
SecuraBio124 enrolled44 locationsNCT06522737